This IgG1 mouse monoclonal (AP3) was generated against human platelets and is specific for PSI/Hybrid (amino acids 50-62) of human glycoprotein IIIa (GPIIIa; CD61). Highlights: Reacts with human glycoprotein IIIaSuitable for non reduced Western Blot, Flow Cytometry, ELISA and Affinity Chromatography Glycoprotein IIb/IIIa, also known as integrin aIIbß3 is an integrin complex found on platelets. The complex acts as a receptor for both fibrogen and von Willebrand factor and helps in platelet activation. Defects in glycoprotein IIb/IIIa cause Glanzmann's thrombasthenia, which is an abnormality in the platelets, or bleeding disorder.