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Apolipoprotein-J Mouse Recombinant
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  • 货号 CYT-1172
  • 品牌 ProSpec ( 经销商 )
  • CAS号 见包装
  • 规格/包装 10ug
  • 单位
  • 储存条件 见包装
  • 现货状态 一个半月

  • 数量

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Clusterin also known as Apolipoprotein J (APO-J) is a 75-80 kD disulfide-linked heterodimeric protein containing about 30% of N-linked carbohydrate rich in sialic acid but truncated forms targeted to the nucleus have also been identified. The precursor polypeptide chain is cleaved proteolytically to remove the 22-mer secretory signal peptide and subsequently between residues 227/228 to generate the a and b chains. These are assembled in anti-parallel to give a heterodimeric molecule in which the cysteine-rich centers are linked by 5 disulfide bridges and are flanked by 2 predicted coiled-coil a-helices and 3 predicted amphipathic a-helices.
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