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Iduronate 2-sulfatase (IDS) is a sulfatase enzyme associated with Hunter syndrome. It encodes a member of the sulfatase family of proteins. Iduronate 2-sulfatase is involved in the lysosomal degradation of the glycosaminoglycans heparan sulfate and dermatan sulfate. The encoded preproprotein is proteolytically processed to generate two polypeptide chains. Mutations in this gene are associated with the X-linked lysosomal storage disease mucopolysaccharidosis type II, also known as Hunter syndrome. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.
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一家老牌抗体原产企业,专注于研发多种指标单克隆抗体和多克隆抗体,产品涉及细胞通路、细胞生物学、神经生物学、表观遗传学、癌症等多个领域;标签抗体和GFP抗体种类丰富;同时专注各类荧光二抗和Trueblot特色产品的开发。