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L1TD1 (ECAT11) is a member of the family of Embryonic Stem Cell Associated Transcripts (ECAT) that play an important role in stem cell biology. ECAT4 (Nanog) is a master regulator for the maintenance of mESC and hESC. ECAT5 was identified to be Embryonic stem cell expressed Ras (ERas), a Ras-like oncogene that is important in regulating mESC proliferation. ECAT9 (GDF3) is an important factor that helps maintain mESC pluripotency by inhibiting bone morphogenetic protein (BMP) signaling. L1TD1 is highly enriched in undifferentiated hESC and L1TD1 is a target gene of Nanog.
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一家老牌抗体原产企业,专注于研发多种指标单克隆抗体和多克隆抗体,产品涉及细胞通路、细胞生物学、神经生物学、表观遗传学、癌症等多个领域;标签抗体和GFP抗体种类丰富;同时专注各类荧光二抗和Trueblot特色产品的开发。