产品描述说明： The CXCR3 protein is a G protein-coupled receptor with selectivity for three chemokines, termed CXCL9/Mig (monokine induced by interferon-gamma), CXCL10/IP10 (interferon-gamma-inducible 10 kDa protein) and CXCL11/I-TAC (interferon-inducible T cell alpha-chemoattractant) (reviewed in 1). Binding of chemokines to this protein induces cellular responses that are involved in leukocyte traffic, most notably integrin activation, cytoskeletal changes and chemotactic migration (2). Similar to other chemokine receptors such as CXCR4, CXCR3 has been implicated in several malignancies as a biomarker of tumor behavior as well as a potential therapeutic target (3). 品牌简介： 一家老牌抗体原产企业，专注于研发多种指标单克隆抗体和多克隆抗体，产品涉及细胞通路、细胞生物学、神经生物学、表观遗传学、癌症等多个领域；标签抗体和GFP抗体种类丰富；同时专注各类荧光二抗和Trueblot特色产品的开发。