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产品描述说明:In humans, Major Histocompatibility Locus (MHC) class II molecules are encoded by three different loci, HLA-DR, -DQ, and -DP, which display ∼70% similarity to each other. Polymorphism is a notable feature of MHC class II genes. HLA-DR, HLA-DP, and HLA-DQ are heterodimeric cell surface glycoproteins comprised of an α (heavy) chain and a β (light) chain. They are expressed on B cells, activated T cells, monocytes/macrophages, dendritic cells, and other non-professional APCs. In conjunction with the CD3/TCR complex and CD4 molecules, HLA-DR is critical for efficient peptide presentation to CD4+ T cells. Variations in the HLA gene expression are crucial to graft survival.
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世界排名前十的抗体生产商,以优质的兔多克隆抗体闻名,所有抗体都经过一系列实验技术的检验,如:ELISA,WB,IP,ChIP,PLA(邻近连接技术),IHC和ICC等;不断生产出新的抗体,产品不仅针对新兴领域的热门蛋白,也包括一直以来缺少高质量检测抗体的经典蛋白。目前已拥有针对2300种目标蛋白而生产出来的近7000种一抗,同时也可提供针对来自27个种属的免疫球蛋白的二抗;抗体定制方面有40年的经验。