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产品描述说明:CD2-associated protein (CD2AP) seems to act as an adapter protein between membrane proteins and the actin cytoskeleton. In collaboration with CBLC, it modulates the rate of RET turnover and may act as regulatory checkpoint that limits the potency of GDNF on neuronal survival. It also controls CBLC function, converting it from an inhibitor to a promoter of RET degradation. CD2AP may play a role in receptor clustering and cytoskeletal polarity in the junction between T-cell and antigen-presenting cell and may anchor the podocyte slit diaphragm to the actin cytoskeleton in renal glomerolus. CD2AP is also required for cytokinesis [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9Y5K6].
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世界排名前十的抗体生产商,以优质的兔多克隆抗体闻名,所有抗体都经过一系列实验技术的检验,如:ELISA,WB,IP,ChIP,PLA(邻近连接技术),IHC和ICC等;不断生产出新的抗体,产品不仅针对新兴领域的热门蛋白,也包括一直以来缺少高质量检测抗体的经典蛋白。目前已拥有针对2300种目标蛋白而生产出来的近7000种一抗,同时也可提供针对来自27个种属的免疫球蛋白的二抗;抗体定制方面有40年的经验。