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产品描述说明:Arsenate resistance protein 2 (ARS2) acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. ARS2 contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and DROSHA, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. ARS2 does not directly confer arsenite resistance but rather modulates arsenic sensitivity. Independently of its activity on miRNAs, it is necessary and sufficient to promote neural stem cell self-renewa and does so by directly binding SOX2 promoter and positively regulating its transcription (By similarity) [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9BXP5].
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世界排名前十的抗体生产商,以优质的兔多克隆抗体闻名,所有抗体都经过一系列实验技术的检验,如:ELISA,WB,IP,ChIP,PLA(邻近连接技术),IHC和ICC等;不断生产出新的抗体,产品不仅针对新兴领域的热门蛋白,也包括一直以来缺少高质量检测抗体的经典蛋白。目前已拥有针对2300种目标蛋白而生产出来的近7000种一抗,同时也可提供针对来自27个种属的免疫球蛋白的二抗;抗体定制方面有40年的经验。