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产品描述说明:76 kDa Ral-interacting protein (RLIP76) can activate, specifically, hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. RLIP76 mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. It can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. It serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q15311].
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世界排名前十的抗体生产商,以优质的兔多克隆抗体闻名,所有抗体都经过一系列实验技术的检验,如:ELISA,WB,IP,ChIP,PLA(邻近连接技术),IHC和ICC等;不断生产出新的抗体,产品不仅针对新兴领域的热门蛋白,也包括一直以来缺少高质量检测抗体的经典蛋白。目前已拥有针对2300种目标蛋白而生产出来的近7000种一抗,同时也可提供针对来自27个种属的免疫球蛋白的二抗;抗体定制方面有40年的经验。