产品描述说明：STIM2 (stromal interaction molecule 2) plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Stim2 functions as a highly sensitive Ca(2+) sensor in the endoplasmic reticulum which activates both store-operated and store-independent Ca(2+)-influx. It regulates basal cytosolic and endoplasmic reticulum Ca(2+) concentrations. Upon mild variations of the endoplasmic reticulum Ca(2+) concentration, STIM2 translocates from the endoplasmic reticulum to the plasma membrane where it probably activates the Ca(2+) release-activated Ca(2+) (CRAC) channels ORAI1, ORAI2 and ORAI. STIM2 may inhibit STIM1-mediated Ca(2+) influx  [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9P246]. 品牌简介： 世界排名前十的抗体生产商，以优质的兔多克隆抗体闻名，所有抗体都经过一系列实验技术的检验，如：ELISA，WB，IP，ChIP，PLA（邻近连接技术），IHC和ICC等；不断生产出新的抗体，产品不仅针对新兴领域的热门蛋白，也包括一直以来缺少高质量检测抗体的经典蛋白。目前已拥有针对2300种目标蛋白而生产出来的近7000种一抗，同时也可提供针对来自27个种属的免疫球蛋白的二抗；抗体定制方面有40年的经验。