产品描述说明：ErbB3, also known as HER3, is a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane-bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation of pathways which lead to cell proliferation or differentiation. Amplification of this gene and/or overexpression of its protein have been reported in numerous cancers, including prostate, bladder, and breast tumors[taken from NCBI Entrez Gene (Gene ID: 2065)]. 品牌简介： 世界排名前十的抗体生产商，以优质的兔多克隆抗体闻名，所有抗体都经过一系列实验技术的检验，如：ELISA，WB，IP，ChIP，PLA（邻近连接技术），IHC和ICC等；不断生产出新的抗体，产品不仅针对新兴领域的热门蛋白，也包括一直以来缺少高质量检测抗体的经典蛋白。目前已拥有针对2300种目标蛋白而生产出来的近7000种一抗，同时也可提供针对来自27个种属的免疫球蛋白的二抗；抗体定制方面有40年的经验。