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Carbazomycin A is a bacterial metabolite that has been found in Streptomyces and has diverse biological activities. It is active against S. aureus, T. asteroides, and T. mentagrophytes (MIC = 12.5 µg/ml for all), as well as the plant pathogenic fungus P. oryzae (MIC = 25 µg/ml). Carbazomycin A is cytotoxic to MCF-7, KB, NCI H187, and Vero cells (ICs = 26.2, 30.1, 18.4, and 32.6 µg/ml, respectively).