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Calcitonin C-Terminal Flanking Peptide, also known as Katacalcin, is a member of the calcitonin gene family. It is a calcium-lowering hormone that can significantly lower plasma calcium level. Calcitonin C-Terminal Flanking Peptide flanks calcitonin on the C-terminal side within the human calcitonin precursor. It specifically binds to the calcitonin receptor of CD14⁺ peripheral blood mononuclear cells.