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Application: Glycopeptide enrichment following protease digestion can be achieved using LudgerClean A Cartridges, enhancing your UHPLC and/or MS signals. Glycopeptides signals are attenuated in a complex mixture, as they are suppressed by non-glycosylated peptides. Enrichment can be performed before or after a labeling reaction. The cartridges contain a unique solid phase extraction (SPE) resin that binds a wide range of glycopeptides and allows the enrichment of these from peptide/glycopeptide mixtures. They are compatible with many leading vacuum manifold SPE handling systems.
Description: For enrichment of glycopeptides after protease digestion (eg. Sequence grade trypsin, pronase). Suitable for enrichment/cleanup after glycopeptide labeling with AQC (6-aminoquinolyl-N-hydroxy-succinimidyl carbamate) and V-tag.