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生产企业：Qiyunbio/其云生物
产品名称：At1g03060(SPI)
产品货号：QA1g03060
基因ID：At1g03060
别称：SPI;BCHA1;At1g03060;F10O3.12
转录本：AT1G03060.1
ORF长度：10806
载体长度：13237
蛋白长度：3601
蛋白分子量：400894 Da
NCBI：839323
Uniprot：F4HZB2
蛋白功能：Involved in cell morphogenesis (PubMed:19392685). May have a function in membrane fusion or membrane composition (PubMed:19392685). Required for salt stress tolerance (PubMed:26133670). Regulates the salt stress-dependent post-transcriptional stabilization, cytoplasmic agglomeration, and localization to P-bodies of a subset of salt stress-regulated mRNAs (PubMed:26133670). {ECO:0000269|PubMed:19392685, ECO:0000269|PubMed:26133670}.
基因摘要：Encodes a WD/BEACH domain protein involved in cell morphogenesis and ribonucleoprotein particle formation. It interacts with the P-body core component DCP2, associates to mRNA processing bodies (P-bodies), and regulates their assembly upon salt stress. It accumulates at the root hair apex via post-Golgi compartments and positively regulates tip growth by maintaining tip-focused vesicle secretion and filamentous-actin integrity.
proteinname：>Protein SPIRRIG (BEACH domain-containing protein A1) (BEACH-domain homolog A1)
proteinseq：MKWATLLKDIKEKVGLAQSSDSDPFPVDLTAPPSSSSSSSSPSFTYPSSSSLHHFNFSPSSRDNHELELDFKRLWEEFRSSSSEKEKEAALNLTVDIFCRLVKRHANVDQLVTMLVETHIFSFVIGRAFVTDIEKLKIGSKTRSLNVEKVLRFFSDVTKEGFSPGANLLTAVEVLVSGPIDKQSLLDSGIFCCLIHVLIALLAYDELSKSKITGDLEVVSAEKDAGYIVLQTRRLEVEGSVVHIMKALASNPSAAQSLIEDDSLESLFNMVANGSITVFSQYKEGLVPLHNIQLHRHAMQILGLLLVNDNGSTARYIRKHHLIKVLLMAVKEFDPSCGDSAYTMGIVDLLLECVELSYRPEAGGVRLREDIRNAHGYHFLVQFALVLSSLPKNPIFVSSNHDSGSDDPEVFHDGENTNSTENADFSSQNFAPSLSRLLDVLVTLAQTGPAEPSVGRASRSSQTKPTGHSRSRTSSVDSIYDETWEQGSGKVKDLEAVQMLQDIFLKAENKDLQAEVLNRMFKIFSSHVENYRLCQELRTVPLLVLNMAGFPSSLQDIILKILEYAVTVVNCVPEQELLSLCCLLQQPITSQLKHTILSFFVKLISFDQQYKKVLREVGVLEVLQDDLKQHKLLIGPDQYSGVSSHSDRKPSSGSFRKNLDTKDAIISSPKLMESGSGKLPVFEVDNTITVGWDCLISLLKKAEANQSSFRAANGVAIILPFLISDAHRSGVLRILSCLITEDTKQVHHDELGAVVDLLKSGMVTGISGHQYKLHDDAKCDTMGALWRIVGVNGSAQRVFGEATGFSLLLTTLHTFQGKREHMDESDLTVYIKLFKYLFRLMTAAVCENAVNRMKLHAVITSQTFFELLAESGLLCVELERQVIQLLLELALEVVVPPFLTSESTALATIPENENTTFVVTTPSGQFNPDKERIYNAGAVRVLIRSLLLFSPKMQLEFLRLLESLARASPFNQENLTSIGCVELLLEIIYPFLAGSSPFLSYALKIVEILGAYRLSPSELRMLFRYVLQMRIMNSGHAIVGMMEKLILMEDTALEHLSLAPFVELDMSKTGHASVQVSLGERSWPPAAGYSFVCWFQFRNFLTTQGKESEASKAGGSSKTRMTSAQQHEQNIFRMFSVGAVSNESPFYAELYFQEDGILTLATSNSHSLSFSGLEIEEGRWHHLAVVHSKPNALAGLFQASVAYVYLDGKLRHTGKLGYSPSPVGKSLQVTVGTPATCARVSDLTWKTRSCYLFEEVLTSGCIGFMYILGRGYKGLFQDADLLRFVPNQACGGGSMAILDSLDTDMTSSSNGQKFDGSNRQGDSKADGSGIVWDLERLGNLAFQLPGKKLIFAFDGTCSEFIRASGNFSLLNLVDPLSAAASPIGGIPRFGRLVGNVSICRQSVIGDTIRPVGGMTVVLALVEAAESRNMLHMALSLLACALHQNPQNVKDMQTIRGYHLLALFLRPKMTLFDMQSLEIFFQIAACEALFSEPKKLESVQSNITMPPTETIFENSYEDLSLSRFRYDSSSVGSHGDMDDFSVPKDSFSHLSELETDIPVETSNCIVLSNADMVEHVLLDWTLWVTSPVSIQIALLGFLENLVSMHWYRNHNLTILRRINLVEHLLVTLQRGDVEVPVLEKLVVLLGCILEDGFLTSELENVVRFVIMTFNPPEVKSRSSLLRESMGKHVIVRNMLLEMLIDLQVTIKAEDLLELWHKIVSSKLITYFLDEAVHPTSMRWIMTLLGVCLASSPNFSLKFRTSGGYQGLLRVLQNFYDSPDIYYILFCLIFGKPVYPRLPEVRMLDFHALVPNDGSYVELKFIELLDSVVAMAKSTYDRLIMQSMLAHQSGNLSQVSASLVAELIEGAEMTGELQGEALMHKTYAARLMGGEASAPAAATSVLRFMVDLAKMCPQFSTACRRAEFVENCADLYFSCVRAAYAVKMAKQLSVKAEEKHINDADDSGSQGSLPHDQDQSTKTSISVGSFPQGQVSLGSEDMSLPANYVVNDKMENILPPPTQDTSKSLQGVEDVKKQDDHHVGPSASSERDFQDFTGNPVQVQATDSQSSASFPMIESPLLSEKSSLKVSFTPSPSPVVALASWLGSNYNESKSSTLGSPSLESYVSVNEVDASSERKSGSQGSSAANAFFTVSPKLLLETDETGYGGGPCSAGASAVLDFMAEALADLVTEQIKAVPVLESILEMVPFYVDPESVLVFQGLCLSRVMNYLERRLLRDDEEDEKKLDKAKWSVNLDAFCWMIVDRVYMGAFSQPAGVLRALEFLLSMLQLANKDGRVEEVTPSGKGLLSLGRATRQLDAYVHSILKNTNRMVLYCFLPSFLITIGEEDLLSQLGLLVESKKRPSPNPATDESGIDISTVLQLLVANRRIIFCPSNLDTDLNCCLCVNLISLLLDQRKSVQNMSLDIVKYLLVHRRSALEDLLVTKPNQGQNFDVLHGGFDKLLTGNLPEFFKWLESSDKIINKVLEQCAAIMWVQYIAGSAKFPGVRIKGMEGRRKREMGRKSRDMSKLDLKHWDQLNERRYALEVLRDAMSTELRVVRQNKYGWILHAESEWQTHLQQLVHERGIFPMRKSKGTEDPEWQLCPIEGPYRMRKKLERCKLKIDSIQNVLDGKLELGEIELPKVKNEDGPVISDTDSEPPFLLSELYDESFLKESDDFKDVASARNGWNDDRASSTNEASLHSALDFGGKSSIASVPITDTTHVKSETGSPRHSSSAKMDETNGREEKSEKELNDDGEYLIRPYLEHLEKIRFRYNCERVVDLDKHDGIFLIGEFCLYVIENFYIDEDGCICEKECEDELSVIDQALGVKKDVSGSSDFHSKSSTSWTTTVKTGAVGGRAWAYGGGAWGKEKMCMTGNLPHPWRMWKLNNVHEILKRDYQLRPVAIEIFSMDGCNDLLVFHKKEREEVFKNLVAMNLPRNSMLDTTISGSAKQESNEGGRLFKLMAKSFSKRWQNGEISNFQYLMHLNTLAGRGYSDLTQYPVFPWVLADYDSESLDFSDPKTFRKLHKPMGCQTPEGEEEFRKRYESWDDPEVPKFHYGSHYSSAGIVLFYLIRLPPFSSENQKLQGGQFDHADRLFNSIKDTWLSAAGKGNTSDVKELIPEFFYMPEFLENRFSLDLGEKQSGEKVGDVFLPPWARGSVREFILKHREALESDYVSENLHHWIDLIFGYKQRGKAAEEAVNVFYHYTYEGNVDIDAVTDPAMKASILAQINHFGQTPKQLFPKAHVKRRTDRKIPLHPLKHSMHLVPHEIRKCSSSISQIITFHDKVLVAGANCFLKPRGYTKYITWGFPDRSLRFMSYDQDKLLSTHENLHESNQIQCAGVSHDGRIVVTGAEDGLVCVWRVSKDGPRGSRRLRLEKALCAHTAKVTCLRVSQPYMMIASGSDDCTVIIWDLSSLSFVRQLPDFPVPISAIYINDLTGEIVTAAGTVLAVWSINGDCLAVANTSQLPSDSVLSVTGSTSSDWLETSWYVTGHQSGAVKVWRMIHCTDPVSAESKTSSSNRTGGLNLGDQVPEYKLILHKVLKFHKQPVTALHLTSDLKQLLSGDSAGQLLSWTVPDETLRASMKQASLKQASLKQASLKQASSV
相关文献PubMed：PMID: 11130712; 27862469; 19392685; 25618824; 26133670
关键词：Cytoplasm;Reference proteome;Repeat;WD repeat
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ORFseq：ATGAAATGGGCAACATTGCTTAAGGACATCAAGGAGAAGGTTGGATTAGCTCAATCCTCTGACTCCGACCCCTTTCCCGTTGACCTAACTGCTCCGCCCTCTTCTTCTTCTTCTTCCTCTTCTCCTTCTTTTACTTACCCCTCCTCTTCTTCTCTTCATCACTTCAACTTCTCTCCTTCAAGCAGAGATAACCATGAGTTGGAGCTGGACTTCAAGAGATTATGGGAAGAGTTTCGTTCATCTAGTTCTGAAAAGGAGAAGGAGGCCGCCTTGAATTTGACCGTCGATATATTTTGTAGATTAGTGAAGCGGCACGCTAATGTAGATCAGTTAGTTACTATGTTAGTAGAAACACATATATTCTCCTTTGTCATTGGGAGAGCATTTGTGACAGATATTGAAAAGTTGAAGATCGGCAGCAAGACAAGGTCACTGAATGTAGAGAAAGTATTAAGGTTCTTTTCAGATGTCACCAAGGAGGGATTTAGTCCTGGTGCAAACCTCTTAACTGCTGTTGAAGTACTTGTATCTGGGCCTATCGACAAACAATCACTACTGGATTCTGGGATATTCTGTTGTCTAATACACGTTCTCATTGCACTTCTAGCATATGATGAACTAAGCAAAAGTAAAATAACTGGTGACTTAGAAGTTGTATCAGCGGAAAAAGATGCTGGATACATAGTTCTCCAGACTAGACGACTTGAGGTGGAGGGTAGTGTTGTTCATATCATGAAAGCATTAGCAAGCAATCCTTCTGCTGCTCAGAGTTTGATTGAAGATGACTCTCTTGAGTCGCTTTTCAATATGGTTGCCAATGGCTCCATTACAGTTTTTTCTCAGTATAAAGAAGGTCTAGTTCCCCTCCATAACATACAACTTCACAGACATGCAATGCAGATCCTTGGACTTCTACTAGTCAATGACAATGGGAGCACAGCAAGATACATACGCAAGCACCATCTGATAAAGGTGCTCTTGATGGCTGTCAAAGAATTTGATCCAAGTTGTGGTGACTCAGCCTACACTATGGGCATTGTGGACTTGTTACTTGAATGTGTAGAACTATCGTACAGACCTGAGGCTGGTGGTGTTAGGCTCCGGGAGGACATACGTAATGCACACGGTTACCACTTTCTTGTTCAGTTTGCCCTGGTTCTATCTTCCTTGCCAAAAAATCCGATTTTTGTGTCCAGTAATCATGATAGTGGTTCCGATGACCCTGAAGTGTTTCATGATGGAGAAAATACAAACAGTACGGAAAATGCTGATTTTTCATCACAAAACTTTGCTCCATCGTTGTCAAGATTGCTTGATGTCCTCGTCACCCTGGCTCAGACTGGTCCAGCTGAGCCATCTGTAGGGAGGGCCTCACGGTCATCCCAAACGAAGCCAACTGGGCATAGCAGAAGTCGAACTTCATCTGTTGACAGTATATACGATGAGACATGGGAACAGGGAAGTGGTAAAGTTAAAGACCTGGAAGCTGTTCAAATGCTGCAAGATATCTTCCTGAAGGCAGAGAATAAGGATCTTCAGGCAGAAGTATTAAATAGAATGTTCAAGATATTCTCGAGCCACGTGGAAAACTATAGATTATGTCAGGAATTAAGAACCGTTCCATTGCTTGTCCTCAATATGGCTGGTTTTCCTTCCTCGCTGCAAGATATAATTCTCAAAATTCTTGAATATGCTGTCACAGTTGTGAATTGTGTTCCAGAGCAAGAATTGTTGTCACTTTGTTGCTTATTGCAACAGCCAATTACATCTCAGTTGAAGCACACCATACTTTCTTTCTTTGTGAAGCTCATATCTTTTGATCAACAATATAAGAAAGTCCTACGTGAAGTTGGTGTTTTGGAAGTCTTACAGGATGATTTGAAGCAGCACAAGCTTCTTATTGGTCCAGATCAGTATAGTGGAGTCTCTAGTCATTCAGATCGGAAGCCTAGCTCAGGTAGCTTCAGAAAGAACTTAGATACTAAAGATGCCATCATCTCATCACCAAAGTTGATGGAATCTGGGTCAGGAAAGTTACCTGTTTTTGAAGTTGACAACACTATTACTGTTGGTTGGGATTGTTTGATCTCTTTGTTAAAGAAAGCTGAGGCTAATCAGTCATCTTTTCGTGCGGCCAATGGGGTGGCGATTATTCTTCCTTTCTTGATATCTGATGCCCATCGAAGTGGCGTTTTGAGGATCTTATCATGTCTAATCACAGAAGACACTAAACAGGTCCATCATGACGAATTAGGAGCTGTTGTCGATTTGTTAAAGAGTGGAATGGTCACTGGTATTTCTGGCCATCAATACAAGCTTCATGATGATGCGAAATGTGATACAATGGGTGCTCTATGGCGTATTGTTGGTGTTAATGGCTCTGCCCAAAGAGTCTTTGGCGAAGCCACTGGTTTCTCTCTTTTATTGACGACCCTTCATACTTTTCAAGGGAAAAGAGAGCACATGGATGAGTCTGACTTGACGGTTTACATCAAATTGTTTAAATATCTGTTTCGCCTTATGACAGCTGCAGTCTGTGAGAATGCTGTTAATAGGATGAAACTCCACGCTGTTATAACGTCTCAGACATTTTTTGAGCTTTTGGCGGAGTCTGGATTGCTGTGTGTTGAGTTGGAAAGGCAGGTTATACAGCTGTTGTTAGAACTTGCACTTGAAGTGGTGGTTCCCCCGTTTTTAACATCAGAGTCAACGGCCCTTGCTACTATACCAGAAAATGAAAACACAACTTTTGTTGTAACAACCCCATCGGGCCAGTTCAATCCTGACAAGGAGAGAATTTACAATGCAGGTGCGGTCAGAGTTCTGATCCGTTCTTTGTTGCTTTTTAGTCCAAAAATGCAGCTAGAATTTTTGAGACTTCTGGAAAGTCTTGCACGTGCCAGTCCATTCAATCAGGAAAACCTCACATCGATTGGTTGCGTGGAACTCTTGTTGGAGATCATTTACCCCTTTCTTGCGGGTTCATCTCCATTTCTTTCTTATGCTTTGAAGATTGTGGAAATTCTTGGAGCGTACAGATTGTCCCCATCTGAGCTCCGAATGCTGTTTAGATATGTTTTGCAAATGAGGATTATGAATTCAGGTCATGCAATAGTTGGCATGATGGAAAAACTAATTCTCATGGAAGACACAGCCTTGGAACATCTATCTCTGGCTCCTTTTGTAGAATTGGATATGAGCAAAACTGGGCATGCTTCTGTTCAGGTGTCCCTGGGAGAAAGATCTTGGCCGCCTGCGGCTGGTTATTCATTTGTTTGTTGGTTCCAGTTTCGTAATTTTTTGACAACCCAAGGAAAAGAATCAGAAGCCTCTAAAGCTGGCGGTTCATCAAAGACGCGCATGACAAGTGCCCAACAACACGAGCAGAACATTTTCCGGATGTTTTCTGTTGGTGCTGTAAGCAATGAAAGTCCATTCTATGCAGAACTTTACTTTCAGGAGGATGGTATTCTGACCCTTGCCACTAGCAATTCACATTCTTTGTCGTTTTCTGGATTGGAGATTGAGGAGGGCAGGTGGCATCACCTTGCTGTTGTTCATAGTAAACCGAATGCTCTTGCTGGACTCTTCCAAGCTAGTGTTGCATATGTCTATCTTGATGGAAAACTAAGGCACACGGGTAAATTGGGGTACTCTCCTTCGCCTGTTGGAAAATCTTTGCAGGTAACAGTTGGAACTCCGGCTACTTGTGCCAGAGTTAGTGATCTGACATGGAAAACACGCTCATGTTATCTTTTTGAGGAGGTGCTCACATCAGGTTGCATTGGTTTCATGTACATTCTTGGTAGGGGGTACAAAGGTCTTTTCCAGGATGCAGACCTCTTACGCTTTGTGCCTAATCAGGCTTGTGGTGGGGGCAGCATGGCTATCCTGGACTCATTAGACACTGACATGACTTCATCGTCGAATGGACAAAAGTTTGATGGAAGCAATAGACAAGGTGACTCCAAGGCAGATGGCAGTGGAATTGTCTGGGATCTTGAGAGGTTGGGAAATCTTGCCTTTCAGTTACCTGGCAAGAAACTGATATTTGCATTTGATGGAACATGCTCGGAGTTCATCCGTGCGTCTGGAAATTTTTCACTCCTCAATCTGGTTGACCCATTGTCTGCTGCTGCTTCTCCAATTGGAGGAATACCACGTTTTGGGCGTCTGGTAGGAAATGTATCTATCTGCAGACAAAGTGTGATTGGTGATACTATCCGACCTGTGGGAGGAATGACTGTTGTACTTGCGCTTGTTGAGGCTGCCGAATCTAGAAATATGCTACATATGGCTCTTTCATTGCTTGCATGTGCGCTTCATCAAAACCCTCAAAATGTGAAGGATATGCAAACCATAAGGGGATATCATTTACTAGCTCTGTTTTTGCGTCCCAAAATGACCCTGTTTGACATGCAGTCTTTGGAGATATTTTTTCAAATTGCAGCATGCGAAGCTTTGTTTTCAGAGCCAAAAAAGTTGGAGAGTGTACAGAGTAATATTACTATGCCACCTACAGAGACTATATTCGAAAACAGTTACGAGGATCTTAGTCTTTCGAGGTTCCGGTACGATAGTTCCTCAGTTGGGTCTCATGGGGATATGGATGACTTTTCTGTTCCCAAGGATTCATTTAGCCATCTCTCTGAGCTAGAAACAGATATCCCTGTTGAAACTTCAAACTGCATTGTCTTATCCAACGCCGATATGGTTGAACATGTCCTTCTGGACTGGACCCTTTGGGTAACATCCCCTGTTTCCATCCAGATTGCTTTACTTGGTTTCCTGGAAAATTTGGTTTCAATGCATTGGTACAGGAATCACAATCTTACAATTCTGCGCAGAATCAATCTGGTAGAACATTTGTTAGTGACACTTCAGAGAGGTGATGTGGAAGTTCCGGTCCTAGAAAAATTAGTTGTTCTGCTAGGATGCATCTTAGAAGACGGATTCCTGACTTCTGAGCTTGAAAATGTCGTTAGGTTTGTGATTATGACATTTAACCCACCTGAAGTGAAGTCACGAAGCTCATTGTTGCGCGAATCAATGGGAAAGCATGTAATTGTGAGAAATATGCTTTTGGAAATGCTCATTGATCTTCAGGTAACCATTAAAGCAGAGGACCTTCTGGAGCTGTGGCATAAGATAGTCTCGTCAAAATTGATAACATACTTCCTCGATGAAGCTGTGCATCCTACTAGTATGAGGTGGATCATGACCCTTCTTGGTGTCTGTCTTGCTTCCTCTCCGAACTTTTCCCTTAAATTTCGAACAAGTGGAGGTTATCAGGGGCTGCTGCGGGTACTTCAAAACTTTTATGATTCCCCAGACATATATTACATACTGTTCTGCTTGATCTTTGGGAAACCTGTTTATCCAAGACTACCGGAAGTTCGAATGTTAGACTTTCATGCTCTAGTGCCAAATGATGGAAGCTATGTGGAGTTAAAGTTCATAGAACTGTTGGATTCAGTGGTGGCAATGGCTAAATCTACTTATGACAGGTTGATCATGCAATCAATGCTAGCCCACCAGTCTGGAAATCTTTCTCAGGTGAGTGCTAGTCTTGTGGCAGAGCTTATAGAGGGGGCAGAAATGACTGGGGAGCTTCAGGGGGAAGCTTTGATGCACAAAACATATGCGGCACGCTTGATGGGTGGCGAAGCGTCAGCTCCTGCTGCTGCAACGTCTGTTCTCCGTTTCATGGTTGACCTTGCAAAGATGTGCCCTCAATTTTCTACTGCTTGCAGACGTGCAGAATTTGTTGAAAATTGTGCTGATCTTTACTTCTCCTGTGTCAGGGCTGCTTATGCTGTGAAGATGGCGAAACAGCTCTCTGTGAAGGCGGAAGAGAAGCATATAAATGATGCTGACGATAGCGGCTCACAAGGAAGCTTGCCTCATGATCAGGATCAGTCCACTAAAACCTCCATCAGTGTTGGAAGCTTCCCTCAAGGGCAGGTCAGTCTTGGTTCCGAAGACATGTCTTTACCTGCAAATTATGTGGTTAATGATAAGATGGAGAACATTCTTCCACCACCAACACAGGACACAAGTAAATCATTACAAGGTGTTGAAGATGTTAAGAAACAAGACGATCATCATGTTGGCCCTTCAGCTTCCAGTGAAAGGGACTTTCAAGATTTTACAGGTAATCCAGTTCAAGTTCAGGCAACAGATTCTCAGAGCTCTGCATCTTTCCCTATGATCGAGTCTCCCCTTTTATCTGAAAAATCAAGTCTCAAAGTCTCATTCACTCCATCACCATCTCCGGTTGTTGCACTTGCATCCTGGCTAGGCTCCAACTATAACGAATCTAAAAGTTCTACCTTGGGTTCTCCTTCCCTTGAATCTTATGTGTCTGTTAATGAAGTTGATGCATCTTCAGAGCGAAAGTCAGGCTCCCAAGGATCTTCGGCTGCCAATGCATTCTTCACAGTTAGCCCAAAACTTCTCCTTGAAACAGATGAAACTGGGTATGGTGGCGGGCCTTGTTCTGCTGGAGCGAGTGCTGTATTAGATTTTATGGCAGAGGCACTTGCTGACTTAGTGACTGAACAGATTAAAGCAGTACCGGTTCTGGAAAGCATATTGGAAATGGTTCCTTTCTATGTTGATCCTGAAAGTGTGCTGGTCTTTCAAGGCTTATGCCTTAGCAGGGTCATGAACTATCTTGAAAGGCGTCTCTTGCGTGATGATGAAGAGGACGAGAAAAAACTGGACAAGGCCAAATGGTCTGTGAATTTGGATGCATTTTGCTGGATGATAGTGGATCGTGTTTATATGGGTGCATTTTCTCAACCCGCTGGTGTTCTTAGGGCTCTAGAGTTCTTGTTATCGATGCTCCAATTAGCTAACAAAGATGGTAGGGTTGAAGAAGTCACTCCTTCAGGGAAAGGTCTTTTATCCCTTGGAAGAGCAACACGACAACTTGATGCTTATGTGCACTCAATCTTGAAAAACACAAATAGAATGGTATTATATTGTTTCCTGCCCTCGTTTTTGATAACTATCGGAGAGGAGGATCTACTATCCCAACTGGGTTTGCTTGTTGAATCTAAGAAGAGGCCATCTCCGAATCCAGCTACTGATGAATCTGGGATTGACATCTCAACAGTTTTGCAATTGTTGGTCGCAAACAGGAGAATCATATTCTGCCCAAGCAACCTTGATACTGATTTGAATTGCTGTTTGTGTGTGAATTTAATCTCCCTTCTCCTTGACCAAAGAAAGAGTGTGCAAAACATGTCACTTGATATTGTCAAATATTTGCTGGTACACCGAAGATCTGCACTTGAGGATTTGCTCGTCACTAAACCAAACCAAGGACAAAACTTTGATGTTCTACATGGGGGTTTTGATAAGTTGTTGACTGGAAATCTACCAGAATTCTTTAAGTGGCTTGAAAGCTCTGATAAGATTATTAACAAAGTACTGGAGCAATGTGCTGCAATTATGTGGGTACAGTACATAGCTGGCTCAGCAAAATTTCCCGGTGTTAGGATAAAAGGCATGGAAGGTCGTCGGAAGAGAGAGATGGGGAGAAAATCACGAGATATGTCAAAGTTAGACCTAAAACATTGGGATCAGTTGAATGAACGAAGATATGCGCTAGAAGTATTGCGTGATGCCATGTCTACTGAGCTTAGAGTAGTTCGGCAAAACAAATATGGTTGGATACTTCATGCTGAGAGTGAGTGGCAAACTCATCTCCAGCAGCTTGTACATGAGCGTGGGATATTCCCAATGCGAAAATCCAAAGGGACTGAAGATCCTGAATGGCAGCTCTGTCCGATTGAAGGTCCATACAGAATGCGCAAAAAGCTTGAACGATGTAAGCTAAAAATTGATAGCATCCAGAATGTTCTTGATGGAAAGTTGGAACTTGGAGAAATTGAGCTTCCCAAAGTCAAAAATGAAGATGGACCAGTTATTTCTGACACAGATTCCGAGCCACCTTTCCTACTCAGTGAACTCTATGATGAGTCGTTTTTGAAAGAGTCTGATGATTTTAAAGATGTCGCTTCCGCCAGAAATGGATGGAATGATGATAGAGCTAGCAGTACAAACGAAGCAAGTCTTCATTCTGCTCTTGATTTTGGTGGAAAATCTAGTATAGCTTCTGTGCCCATAACAGACACCACACATGTGAAATCTGAGACTGGCTCTCCAAGACATTCATCCTCTGCTAAAATGGATGAAACTAATGGCCGGGAGGAAAAATCAGAGAAGGAACTGAATGATGATGGTGAATATTTGATTAGACCTTATCTTGAGCATCTTGAAAAGATTCGGTTCAGATACAACTGTGAGAGAGTTGTTGATCTCGACAAGCATGATGGAATCTTCTTAATAGGGGAATTCTGTCTGTATGTGATAGAAAACTTTTACATTGACGAAGATGGGTGTATTTGTGAGAAGGAATGCGAAGATGAGTTATCCGTTATTGATCAAGCGTTGGGTGTGAAAAAAGATGTCTCTGGAAGCTCGGATTTCCATTCCAAGTCTAGCACATCATGGACTACAACAGTGAAAACAGGAGCAGTAGGGGGAAGAGCATGGGCATATGGTGGTGGTGCTTGGGGAAAAGAAAAAATGTGCATGACTGGTAACTTGCCGCATCCTTGGCGTATGTGGAAGCTTAATAATGTTCATGAAATTTTGAAACGTGATTACCAGCTGCGTCCGGTTGCTATTGAGATATTTAGCATGGATGGGTGTAATGATCTCCTTGTGTTCCACAAGAAAGAGAGGGAAGAAGTTTTCAAAAATCTGGTTGCCATGAATCTTCCAAGGAACAGCATGCTCGACACAACCATTTCAGGATCAGCTAAACAGGAAAGTAACGAGGGAGGCCGGCTTTTCAAATTAATGGCGAAGTCTTTCTCGAAAAGATGGCAAAATGGAGAAATCAGCAATTTCCAATACCTAATGCATCTCAATACCTTAGCAGGACGTGGATACAGTGATCTCACACAGTATCCTGTATTTCCGTGGGTTCTAGCAGATTATGATAGCGAGAGTCTTGATTTTTCAGATCCAAAAACATTCCGCAAGCTTCACAAACCAATGGGTTGCCAGACACCTGAAGGAGAAGAAGAATTTAGAAAACGATATGAGAGCTGGGATGACCCCGAGGTTCCAAAATTTCATTATGGTTCTCACTATTCAAGTGCTGGAATTGTTCTGTTTTACCTTATTCGCCTCCCACCATTCAGTTCTGAAAATCAGAAGCTCCAGGGCGGTCAGTTTGATCATGCTGATAGACTCTTCAATAGTATTAAAGATACTTGGCTAAGTGCAGCAGGAAAGGGAAATACTTCAGACGTGAAAGAACTAATTCCTGAATTCTTCTACATGCCCGAGTTTTTGGAAAATAGATTCAGCCTTGATCTGGGTGAAAAACAGTCAGGAGAGAAGGTTGGTGATGTCTTTTTACCTCCTTGGGCTAGAGGTAGTGTTCGTGAGTTCATCCTCAAACACAGAGAAGCGTTGGAGTCAGACTATGTCTCAGAGAATTTGCATCATTGGATAGATCTCATATTTGGGTACAAACAGAGAGGAAAGGCTGCAGAAGAAGCTGTGAATGTTTTCTATCATTACACATACGAAGGAAATGTTGATATTGATGCAGTTACCGACCCCGCAATGAAAGCTTCTATACTAGCGCAGATTAATCATTTTGGGCAAACTCCTAAACAACTATTCCCGAAAGCTCATGTCAAAAGAAGAACAGACAGAAAAATTCCTCTCCACCCTCTGAAACACTCGATGCATCTAGTTCCTCACGAAATACGTAAATGCTCATCTTCTATAAGCCAGATCATTACTTTCCACGACAAGGTACTCGTTGCTGGAGCCAACTGTTTCCTGAAACCTAGAGGCTATACCAAATACATAACATGGGGATTCCCAGACAGGAGCTTGAGATTTATGAGCTATGATCAGGACAAACTGCTATCAACCCATGAAAATCTCCATGAAAGCAACCAGATTCAGTGTGCTGGTGTAAGTCACGATGGGCGCATTGTGGTCACTGGAGCAGAGGATGGTTTAGTGTGCGTGTGGAGAGTAAGCAAGGATGGTCCACGTGGTTCACGGCGTTTACGGTTAGAGAAAGCCCTATGTGCTCACACAGCTAAAGTCACATGTCTACGTGTAAGCCAACCGTACATGATGATTGCAAGTGGGTCAGACGACTGTACAGTCATCATATGGGATCTCAGTTCATTGAGTTTTGTGAGGCAGCTTCCTGACTTCCCAGTTCCCATTTCAGCAATCTACATAAACGACCTTACTGGGGAAATTGTAACCGCTGCTGGAACTGTCCTTGCGGTTTGGAGCATCAATGGCGATTGCCTTGCTGTGGCTAACACATCGCAGTTACCATCTGATTCGGTATTATCAGTAACAGGCTCAACATCTTCCGACTGGCTTGAGACAAGCTGGTATGTAACTGGTCATCAGAGTGGAGCAGTTAAAGTATGGCGGATGATTCATTGTACTGATCCGGTGAGTGCCGAGAGCAAAACAAGTAGTAGCAACAGAACAGGAGGGCTGAATTTGGGTGATCAAGTGCCAGAATACAAGTTGATTCTACACAAGGTGTTGAAATTCCACAAGCAACCAGTCACCGCGCTCCATCTCACAAGCGACCTGAAGCAGTTACTAAGCGGTGATTCAGCTGGACAGTTACTTTCATGGACAGTACCAGATGAGACATTAAGAGCTTCAATGAAACAAGCTTCATTAAAACAGGCTTCATTAAAACAGGCTTCACTGAAACAGGCTTCATCGGTTTAG
产品名称：At1g03060(SPI)
产品货号：QA1g03060
基因ID：At1g03060
别称：SPI;BCHA1;At1g03060;F10O3.12
转录本：AT1G03060.1
ORF长度：10806
载体长度：13237
蛋白长度：3601
蛋白分子量：400894 Da
NCBI：839323
Uniprot：F4HZB2
蛋白功能：Involved in cell morphogenesis (PubMed:19392685). May have a function in membrane fusion or membrane composition (PubMed:19392685). Required for salt stress tolerance (PubMed:26133670). Regulates the salt stress-dependent post-transcriptional stabilization, cytoplasmic agglomeration, and localization to P-bodies of a subset of salt stress-regulated mRNAs (PubMed:26133670). {ECO:0000269|PubMed:19392685, ECO:0000269|PubMed:26133670}.
基因摘要：Encodes a WD/BEACH domain protein involved in cell morphogenesis and ribonucleoprotein particle formation. It interacts with the P-body core component DCP2, associates to mRNA processing bodies (P-bodies), and regulates their assembly upon salt stress. It accumulates at the root hair apex via post-Golgi compartments and positively regulates tip growth by maintaining tip-focused vesicle secretion and filamentous-actin integrity.
proteinname：>Protein SPIRRIG (BEACH domain-containing protein A1) (BEACH-domain homolog A1)
proteinseq：MKWATLLKDIKEKVGLAQSSDSDPFPVDLTAPPSSSSSSSSPSFTYPSSSSLHHFNFSPSSRDNHELELDFKRLWEEFRSSSSEKEKEAALNLTVDIFCRLVKRHANVDQLVTMLVETHIFSFVIGRAFVTDIEKLKIGSKTRSLNVEKVLRFFSDVTKEGFSPGANLLTAVEVLVSGPIDKQSLLDSGIFCCLIHVLIALLAYDELSKSKITGDLEVVSAEKDAGYIVLQTRRLEVEGSVVHIMKALASNPSAAQSLIEDDSLESLFNMVANGSITVFSQYKEGLVPLHNIQLHRHAMQILGLLLVNDNGSTARYIRKHHLIKVLLMAVKEFDPSCGDSAYTMGIVDLLLECVELSYRPEAGGVRLREDIRNAHGYHFLVQFALVLSSLPKNPIFVSSNHDSGSDDPEVFHDGENTNSTENADFSSQNFAPSLSRLLDVLVTLAQTGPAEPSVGRASRSSQTKPTGHSRSRTSSVDSIYDETWEQGSGKVKDLEAVQMLQDIFLKAENKDLQAEVLNRMFKIFSSHVENYRLCQELRTVPLLVLNMAGFPSSLQDIILKILEYAVTVVNCVPEQELLSLCCLLQQPITSQLKHTILSFFVKLISFDQQYKKVLREVGVLEVLQDDLKQHKLLIGPDQYSGVSSHSDRKPSSGSFRKNLDTKDAIISSPKLMESGSGKLPVFEVDNTITVGWDCLISLLKKAEANQSSFRAANGVAIILPFLISDAHRSGVLRILSCLITEDTKQVHHDELGAVVDLLKSGMVTGISGHQYKLHDDAKCDTMGALWRIVGVNGSAQRVFGEATGFSLLLTTLHTFQGKREHMDESDLTVYIKLFKYLFRLMTAAVCENAVNRMKLHAVITSQTFFELLAESGLLCVELERQVIQLLLELALEVVVPPFLTSESTALATIPENENTTFVVTTPSGQFNPDKERIYNAGAVRVLIRSLLLFSPKMQLEFLRLLESLARASPFNQENLTSIGCVELLLEIIYPFLAGSSPFLSYALKIVEILGAYRLSPSELRMLFRYVLQMRIMNSGHAIVGMMEKLILMEDTALEHLSLAPFVELDMSKTGHASVQVSLGERSWPPAAGYSFVCWFQFRNFLTTQGKESEASKAGGSSKTRMTSAQQHEQNIFRMFSVGAVSNESPFYAELYFQEDGILTLATSNSHSLSFSGLEIEEGRWHHLAVVHSKPNALAGLFQASVAYVYLDGKLRHTGKLGYSPSPVGKSLQVTVGTPATCARVSDLTWKTRSCYLFEEVLTSGCIGFMYILGRGYKGLFQDADLLRFVPNQACGGGSMAILDSLDTDMTSSSNGQKFDGSNRQGDSKADGSGIVWDLERLGNLAFQLPGKKLIFAFDGTCSEFIRASGNFSLLNLVDPLSAAASPIGGIPRFGRLVGNVSICRQSVIGDTIRPVGGMTVVLALVEAAESRNMLHMALSLLACALHQNPQNVKDMQTIRGYHLLALFLRPKMTLFDMQSLEIFFQIAACEALFSEPKKLESVQSNITMPPTETIFENSYEDLSLSRFRYDSSSVGSHGDMDDFSVPKDSFSHLSELETDIPVETSNCIVLSNADMVEHVLLDWTLWVTSPVSIQIALLGFLENLVSMHWYRNHNLTILRRINLVEHLLVTLQRGDVEVPVLEKLVVLLGCILEDGFLTSELENVVRFVIMTFNPPEVKSRSSLLRESMGKHVIVRNMLLEMLIDLQVTIKAEDLLELWHKIVSSKLITYFLDEAVHPTSMRWIMTLLGVCLASSPNFSLKFRTSGGYQGLLRVLQNFYDSPDIYYILFCLIFGKPVYPRLPEVRMLDFHALVPNDGSYVELKFIELLDSVVAMAKSTYDRLIMQSMLAHQSGNLSQVSASLVAELIEGAEMTGELQGEALMHKTYAARLMGGEASAPAAATSVLRFMVDLAKMCPQFSTACRRAEFVENCADLYFSCVRAAYAVKMAKQLSVKAEEKHINDADDSGSQGSLPHDQDQSTKTSISVGSFPQGQVSLGSEDMSLPANYVVNDKMENILPPPTQDTSKSLQGVEDVKKQDDHHVGPSASSERDFQDFTGNPVQVQATDSQSSASFPMIESPLLSEKSSLKVSFTPSPSPVVALASWLGSNYNESKSSTLGSPSLESYVSVNEVDASSERKSGSQGSSAANAFFTVSPKLLLETDETGYGGGPCSAGASAVLDFMAEALADLVTEQIKAVPVLESILEMVPFYVDPESVLVFQGLCLSRVMNYLERRLLRDDEEDEKKLDKAKWSVNLDAFCWMIVDRVYMGAFSQPAGVLRALEFLLSMLQLANKDGRVEEVTPSGKGLLSLGRATRQLDAYVHSILKNTNRMVLYCFLPSFLITIGEEDLLSQLGLLVESKKRPSPNPATDESGIDISTVLQLLVANRRIIFCPSNLDTDLNCCLCVNLISLLLDQRKSVQNMSLDIVKYLLVHRRSALEDLLVTKPNQGQNFDVLHGGFDKLLTGNLPEFFKWLESSDKIINKVLEQCAAIMWVQYIAGSAKFPGVRIKGMEGRRKREMGRKSRDMSKLDLKHWDQLNERRYALEVLRDAMSTELRVVRQNKYGWILHAESEWQTHLQQLVHERGIFPMRKSKGTEDPEWQLCPIEGPYRMRKKLERCKLKIDSIQNVLDGKLELGEIELPKVKNEDGPVISDTDSEPPFLLSELYDESFLKESDDFKDVASARNGWNDDRASSTNEASLHSALDFGGKSSIASVPITDTTHVKSETGSPRHSSSAKMDETNGREEKSEKELNDDGEYLIRPYLEHLEKIRFRYNCERVVDLDKHDGIFLIGEFCLYVIENFYIDEDGCICEKECEDELSVIDQALGVKKDVSGSSDFHSKSSTSWTTTVKTGAVGGRAWAYGGGAWGKEKMCMTGNLPHPWRMWKLNNVHEILKRDYQLRPVAIEIFSMDGCNDLLVFHKKEREEVFKNLVAMNLPRNSMLDTTISGSAKQESNEGGRLFKLMAKSFSKRWQNGEISNFQYLMHLNTLAGRGYSDLTQYPVFPWVLADYDSESLDFSDPKTFRKLHKPMGCQTPEGEEEFRKRYESWDDPEVPKFHYGSHYSSAGIVLFYLIRLPPFSSENQKLQGGQFDHADRLFNSIKDTWLSAAGKGNTSDVKELIPEFFYMPEFLENRFSLDLGEKQSGEKVGDVFLPPWARGSVREFILKHREALESDYVSENLHHWIDLIFGYKQRGKAAEEAVNVFYHYTYEGNVDIDAVTDPAMKASILAQINHFGQTPKQLFPKAHVKRRTDRKIPLHPLKHSMHLVPHEIRKCSSSISQIITFHDKVLVAGANCFLKPRGYTKYITWGFPDRSLRFMSYDQDKLLSTHENLHESNQIQCAGVSHDGRIVVTGAEDGLVCVWRVSKDGPRGSRRLRLEKALCAHTAKVTCLRVSQPYMMIASGSDDCTVIIWDLSSLSFVRQLPDFPVPISAIYINDLTGEIVTAAGTVLAVWSINGDCLAVANTSQLPSDSVLSVTGSTSSDWLETSWYVTGHQSGAVKVWRMIHCTDPVSAESKTSSSNRTGGLNLGDQVPEYKLILHKVLKFHKQPVTALHLTSDLKQLLSGDSAGQLLSWTVPDETLRASMKQASLKQASLKQASLKQASSV
相关文献PubMed：PMID: 11130712; 27862469; 19392685; 25618824; 26133670
关键词：Cytoplasm;Reference proteome;Repeat;WD repeat
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ORFseq：ATGAAATGGGCAACATTGCTTAAGGACATCAAGGAGAAGGTTGGATTAGCTCAATCCTCTGACTCCGACCCCTTTCCCGTTGACCTAACTGCTCCGCCCTCTTCTTCTTCTTCTTCCTCTTCTCCTTCTTTTACTTACCCCTCCTCTTCTTCTCTTCATCACTTCAACTTCTCTCCTTCAAGCAGAGATAACCATGAGTTGGAGCTGGACTTCAAGAGATTATGGGAAGAGTTTCGTTCATCTAGTTCTGAAAAGGAGAAGGAGGCCGCCTTGAATTTGACCGTCGATATATTTTGTAGATTAGTGAAGCGGCACGCTAATGTAGATCAGTTAGTTACTATGTTAGTAGAAACACATATATTCTCCTTTGTCATTGGGAGAGCATTTGTGACAGATATTGAAAAGTTGAAGATCGGCAGCAAGACAAGGTCACTGAATGTAGAGAAAGTATTAAGGTTCTTTTCAGATGTCACCAAGGAGGGATTTAGTCCTGGTGCAAACCTCTTAACTGCTGTTGAAGTACTTGTATCTGGGCCTATCGACAAACAATCACTACTGGATTCTGGGATATTCTGTTGTCTAATACACGTTCTCATTGCACTTCTAGCATATGATGAACTAAGCAAAAGTAAAATAACTGGTGACTTAGAAGTTGTATCAGCGGAAAAAGATGCTGGATACATAGTTCTCCAGACTAGACGACTTGAGGTGGAGGGTAGTGTTGTTCATATCATGAAAGCATTAGCAAGCAATCCTTCTGCTGCTCAGAGTTTGATTGAAGATGACTCTCTTGAGTCGCTTTTCAATATGGTTGCCAATGGCTCCATTACAGTTTTTTCTCAGTATAAAGAAGGTCTAGTTCCCCTCCATAACATACAACTTCACAGACATGCAATGCAGATCCTTGGACTTCTACTAGTCAATGACAATGGGAGCACAGCAAGATACATACGCAAGCACCATCTGATAAAGGTGCTCTTGATGGCTGTCAAAGAATTTGATCCAAGTTGTGGTGACTCAGCCTACACTATGGGCATTGTGGACTTGTTACTTGAATGTGTAGAACTATCGTACAGACCTGAGGCTGGTGGTGTTAGGCTCCGGGAGGACATACGTAATGCACACGGTTACCACTTTCTTGTTCAGTTTGCCCTGGTTCTATCTTCCTTGCCAAAAAATCCGATTTTTGTGTCCAGTAATCATGATAGTGGTTCCGATGACCCTGAAGTGTTTCATGATGGAGAAAATACAAACAGTACGGAAAATGCTGATTTTTCATCACAAAACTTTGCTCCATCGTTGTCAAGATTGCTTGATGTCCTCGTCACCCTGGCTCAGACTGGTCCAGCTGAGCCATCTGTAGGGAGGGCCTCACGGTCATCCCAAACGAAGCCAACTGGGCATAGCAGAAGTCGAACTTCATCTGTTGACAGTATATACGATGAGACATGGGAACAGGGAAGTGGTAAAGTTAAAGACCTGGAAGCTGTTCAAATGCTGCAAGATATCTTCCTGAAGGCAGAGAATAAGGATCTTCAGGCAGAAGTATTAAATAGAATGTTCAAGATATTCTCGAGCCACGTGGAAAACTATAGATTATGTCAGGAATTAAGAACCGTTCCATTGCTTGTCCTCAATATGGCTGGTTTTCCTTCCTCGCTGCAAGATATAATTCTCAAAATTCTTGAATATGCTGTCACAGTTGTGAATTGTGTTCCAGAGCAAGAATTGTTGTCACTTTGTTGCTTATTGCAACAGCCAATTACATCTCAGTTGAAGCACACCATACTTTCTTTCTTTGTGAAGCTCATATCTTTTGATCAACAATATAAGAAAGTCCTACGTGAAGTTGGTGTTTTGGAAGTCTTACAGGATGATTTGAAGCAGCACAAGCTTCTTATTGGTCCAGATCAGTATAGTGGAGTCTCTAGTCATTCAGATCGGAAGCCTAGCTCAGGTAGCTTCAGAAAGAACTTAGATACTAAAGATGCCATCATCTCATCACCAAAGTTGATGGAATCTGGGTCAGGAAAGTTACCTGTTTTTGAAGTTGACAACACTATTACTGTTGGTTGGGATTGTTTGATCTCTTTGTTAAAGAAAGCTGAGGCTAATCAGTCATCTTTTCGTGCGGCCAATGGGGTGGCGATTATTCTTCCTTTCTTGATATCTGATGCCCATCGAAGTGGCGTTTTGAGGATCTTATCATGTCTAATCACAGAAGACACTAAACAGGTCCATCATGACGAATTAGGAGCTGTTGTCGATTTGTTAAAGAGTGGAATGGTCACTGGTATTTCTGGCCATCAATACAAGCTTCATGATGATGCGAAATGTGATACAATGGGTGCTCTATGGCGTATTGTTGGTGTTAATGGCTCTGCCCAAAGAGTCTTTGGCGAAGCCACTGGTTTCTCTCTTTTATTGACGACCCTTCATACTTTTCAAGGGAAAAGAGAGCACATGGATGAGTCTGACTTGACGGTTTACATCAAATTGTTTAAATATCTGTTTCGCCTTATGACAGCTGCAGTCTGTGAGAATGCTGTTAATAGGATGAAACTCCACGCTGTTATAACGTCTCAGACATTTTTTGAGCTTTTGGCGGAGTCTGGATTGCTGTGTGTTGAGTTGGAAAGGCAGGTTATACAGCTGTTGTTAGAACTTGCACTTGAAGTGGTGGTTCCCCCGTTTTTAACATCAGAGTCAACGGCCCTTGCTACTATACCAGAAAATGAAAACACAACTTTTGTTGTAACAACCCCATCGGGCCAGTTCAATCCTGACAAGGAGAGAATTTACAATGCAGGTGCGGTCAGAGTTCTGATCCGTTCTTTGTTGCTTTTTAGTCCAAAAATGCAGCTAGAATTTTTGAGACTTCTGGAAAGTCTTGCACGTGCCAGTCCATTCAATCAGGAAAACCTCACATCGATTGGTTGCGTGGAACTCTTGTTGGAGATCATTTACCCCTTTCTTGCGGGTTCATCTCCATTTCTTTCTTATGCTTTGAAGATTGTGGAAATTCTTGGAGCGTACAGATTGTCCCCATCTGAGCTCCGAATGCTGTTTAGATATGTTTTGCAAATGAGGATTATGAATTCAGGTCATGCAATAGTTGGCATGATGGAAAAACTAATTCTCATGGAAGACACAGCCTTGGAACATCTATCTCTGGCTCCTTTTGTAGAATTGGATATGAGCAAAACTGGGCATGCTTCTGTTCAGGTGTCCCTGGGAGAAAGATCTTGGCCGCCTGCGGCTGGTTATTCATTTGTTTGTTGGTTCCAGTTTCGTAATTTTTTGACAACCCAAGGAAAAGAATCAGAAGCCTCTAAAGCTGGCGGTTCATCAAAGACGCGCATGACAAGTGCCCAACAACACGAGCAGAACATTTTCCGGATGTTTTCTGTTGGTGCTGTAAGCAATGAAAGTCCATTCTATGCAGAACTTTACTTTCAGGAGGATGGTATTCTGACCCTTGCCACTAGCAATTCACATTCTTTGTCGTTTTCTGGATTGGAGATTGAGGAGGGCAGGTGGCATCACCTTGCTGTTGTTCATAGTAAACCGAATGCTCTTGCTGGACTCTTCCAAGCTAGTGTTGCATATGTCTATCTTGATGGAAAACTAAGGCACACGGGTAAATTGGGGTACTCTCCTTCGCCTGTTGGAAAATCTTTGCAGGTAACAGTTGGAACTCCGGCTACTTGTGCCAGAGTTAGTGATCTGACATGGAAAACACGCTCATGTTATCTTTTTGAGGAGGTGCTCACATCAGGTTGCATTGGTTTCATGTACATTCTTGGTAGGGGGTACAAAGGTCTTTTCCAGGATGCAGACCTCTTACGCTTTGTGCCTAATCAGGCTTGTGGTGGGGGCAGCATGGCTATCCTGGACTCATTAGACACTGACATGACTTCATCGTCGAATGGACAAAAGTTTGATGGAAGCAATAGACAAGGTGACTCCAAGGCAGATGGCAGTGGAATTGTCTGGGATCTTGAGAGGTTGGGAAATCTTGCCTTTCAGTTACCTGGCAAGAAACTGATATTTGCATTTGATGGAACATGCTCGGAGTTCATCCGTGCGTCTGGAAATTTTTCACTCCTCAATCTGGTTGACCCATTGTCTGCTGCTGCTTCTCCAATTGGAGGAATACCACGTTTTGGGCGTCTGGTAGGAAATGTATCTATCTGCAGACAAAGTGTGATTGGTGATACTATCCGACCTGTGGGAGGAATGACTGTTGTACTTGCGCTTGTTGAGGCTGCCGAATCTAGAAATATGCTACATATGGCTCTTTCATTGCTTGCATGTGCGCTTCATCAAAACCCTCAAAATGTGAAGGATATGCAAACCATAAGGGGATATCATTTACTAGCTCTGTTTTTGCGTCCCAAAATGACCCTGTTTGACATGCAGTCTTTGGAGATATTTTTTCAAATTGCAGCATGCGAAGCTTTGTTTTCAGAGCCAAAAAAGTTGGAGAGTGTACAGAGTAATATTACTATGCCACCTACAGAGACTATATTCGAAAACAGTTACGAGGATCTTAGTCTTTCGAGGTTCCGGTACGATAGTTCCTCAGTTGGGTCTCATGGGGATATGGATGACTTTTCTGTTCCCAAGGATTCATTTAGCCATCTCTCTGAGCTAGAAACAGATATCCCTGTTGAAACTTCAAACTGCATTGTCTTATCCAACGCCGATATGGTTGAACATGTCCTTCTGGACTGGACCCTTTGGGTAACATCCCCTGTTTCCATCCAGATTGCTTTACTTGGTTTCCTGGAAAATTTGGTTTCAATGCATTGGTACAGGAATCACAATCTTACAATTCTGCGCAGAATCAATCTGGTAGAACATTTGTTAGTGACACTTCAGAGAGGTGATGTGGAAGTTCCGGTCCTAGAAAAATTAGTTGTTCTGCTAGGATGCATCTTAGAAGACGGATTCCTGACTTCTGAGCTTGAAAATGTCGTTAGGTTTGTGATTATGACATTTAACCCACCTGAAGTGAAGTCACGAAGCTCATTGTTGCGCGAATCAATGGGAAAGCATGTAATTGTGAGAAATATGCTTTTGGAAATGCTCATTGATCTTCAGGTAACCATTAAAGCAGAGGACCTTCTGGAGCTGTGGCATAAGATAGTCTCGTCAAAATTGATAACATACTTCCTCGATGAAGCTGTGCATCCTACTAGTATGAGGTGGATCATGACCCTTCTTGGTGTCTGTCTTGCTTCCTCTCCGAACTTTTCCCTTAAATTTCGAACAAGTGGAGGTTATCAGGGGCTGCTGCGGGTACTTCAAAACTTTTATGATTCCCCAGACATATATTACATACTGTTCTGCTTGATCTTTGGGAAACCTGTTTATCCAAGACTACCGGAAGTTCGAATGTTAGACTTTCATGCTCTAGTGCCAAATGATGGAAGCTATGTGGAGTTAAAGTTCATAGAACTGTTGGATTCAGTGGTGGCAATGGCTAAATCTACTTATGACAGGTTGATCATGCAATCAATGCTAGCCCACCAGTCTGGAAATCTTTCTCAGGTGAGTGCTAGTCTTGTGGCAGAGCTTATAGAGGGGGCAGAAATGACTGGGGAGCTTCAGGGGGAAGCTTTGATGCACAAAACATATGCGGCACGCTTGATGGGTGGCGAAGCGTCAGCTCCTGCTGCTGCAACGTCTGTTCTCCGTTTCATGGTTGACCTTGCAAAGATGTGCCCTCAATTTTCTACTGCTTGCAGACGTGCAGAATTTGTTGAAAATTGTGCTGATCTTTACTTCTCCTGTGTCAGGGCTGCTTATGCTGTGAAGATGGCGAAACAGCTCTCTGTGAAGGCGGAAGAGAAGCATATAAATGATGCTGACGATAGCGGCTCACAAGGAAGCTTGCCTCATGATCAGGATCAGTCCACTAAAACCTCCATCAGTGTTGGAAGCTTCCCTCAAGGGCAGGTCAGTCTTGGTTCCGAAGACATGTCTTTACCTGCAAATTATGTGGTTAATGATAAGATGGAGAACATTCTTCCACCACCAACACAGGACACAAGTAAATCATTACAAGGTGTTGAAGATGTTAAGAAACAAGACGATCATCATGTTGGCCCTTCAGCTTCCAGTGAAAGGGACTTTCAAGATTTTACAGGTAATCCAGTTCAAGTTCAGGCAACAGATTCTCAGAGCTCTGCATCTTTCCCTATGATCGAGTCTCCCCTTTTATCTGAAAAATCAAGTCTCAAAGTCTCATTCACTCCATCACCATCTCCGGTTGTTGCACTTGCATCCTGGCTAGGCTCCAACTATAACGAATCTAAAAGTTCTACCTTGGGTTCTCCTTCCCTTGAATCTTATGTGTCTGTTAATGAAGTTGATGCATCTTCAGAGCGAAAGTCAGGCTCCCAAGGATCTTCGGCTGCCAATGCATTCTTCACAGTTAGCCCAAAACTTCTCCTTGAAACAGATGAAACTGGGTATGGTGGCGGGCCTTGTTCTGCTGGAGCGAGTGCTGTATTAGATTTTATGGCAGAGGCACTTGCTGACTTAGTGACTGAACAGATTAAAGCAGTACCGGTTCTGGAAAGCATATTGGAAATGGTTCCTTTCTATGTTGATCCTGAAAGTGTGCTGGTCTTTCAAGGCTTATGCCTTAGCAGGGTCATGAACTATCTTGAAAGGCGTCTCTTGCGTGATGATGAAGAGGACGAGAAAAAACTGGACAAGGCCAAATGGTCTGTGAATTTGGATGCATTTTGCTGGATGATAGTGGATCGTGTTTATATGGGTGCATTTTCTCAACCCGCTGGTGTTCTTAGGGCTCTAGAGTTCTTGTTATCGATGCTCCAATTAGCTAACAAAGATGGTAGGGTTGAAGAAGTCACTCCTTCAGGGAAAGGTCTTTTATCCCTTGGAAGAGCAACACGACAACTTGATGCTTATGTGCACTCAATCTTGAAAAACACAAATAGAATGGTATTATATTGTTTCCTGCCCTCGTTTTTGATAACTATCGGAGAGGAGGATCTACTATCCCAACTGGGTTTGCTTGTTGAATCTAAGAAGAGGCCATCTCCGAATCCAGCTACTGATGAATCTGGGATTGACATCTCAACAGTTTTGCAATTGTTGGTCGCAAACAGGAGAATCATATTCTGCCCAAGCAACCTTGATACTGATTTGAATTGCTGTTTGTGTGTGAATTTAATCTCCCTTCTCCTTGACCAAAGAAAGAGTGTGCAAAACATGTCACTTGATATTGTCAAATATTTGCTGGTACACCGAAGATCTGCACTTGAGGATTTGCTCGTCACTAAACCAAACCAAGGACAAAACTTTGATGTTCTACATGGGGGTTTTGATAAGTTGTTGACTGGAAATCTACCAGAATTCTTTAAGTGGCTTGAAAGCTCTGATAAGATTATTAACAAAGTACTGGAGCAATGTGCTGCAATTATGTGGGTACAGTACATAGCTGGCTCAGCAAAATTTCCCGGTGTTAGGATAAAAGGCATGGAAGGTCGTCGGAAGAGAGAGATGGGGAGAAAATCACGAGATATGTCAAAGTTAGACCTAAAACATTGGGATCAGTTGAATGAACGAAGATATGCGCTAGAAGTATTGCGTGATGCCATGTCTACTGAGCTTAGAGTAGTTCGGCAAAACAAATATGGTTGGATACTTCATGCTGAGAGTGAGTGGCAAACTCATCTCCAGCAGCTTGTACATGAGCGTGGGATATTCCCAATGCGAAAATCCAAAGGGACTGAAGATCCTGAATGGCAGCTCTGTCCGATTGAAGGTCCATACAGAATGCGCAAAAAGCTTGAACGATGTAAGCTAAAAATTGATAGCATCCAGAATGTTCTTGATGGAAAGTTGGAACTTGGAGAAATTGAGCTTCCCAAAGTCAAAAATGAAGATGGACCAGTTATTTCTGACACAGATTCCGAGCCACCTTTCCTACTCAGTGAACTCTATGATGAGTCGTTTTTGAAAGAGTCTGATGATTTTAAAGATGTCGCTTCCGCCAGAAATGGATGGAATGATGATAGAGCTAGCAGTACAAACGAAGCAAGTCTTCATTCTGCTCTTGATTTTGGTGGAAAATCTAGTATAGCTTCTGTGCCCATAACAGACACCACACATGTGAAATCTGAGACTGGCTCTCCAAGACATTCATCCTCTGCTAAAATGGATGAAACTAATGGCCGGGAGGAAAAATCAGAGAAGGAACTGAATGATGATGGTGAATATTTGATTAGACCTTATCTTGAGCATCTTGAAAAGATTCGGTTCAGATACAACTGTGAGAGAGTTGTTGATCTCGACAAGCATGATGGAATCTTCTTAATAGGGGAATTCTGTCTGTATGTGATAGAAAACTTTTACATTGACGAAGATGGGTGTATTTGTGAGAAGGAATGCGAAGATGAGTTATCCGTTATTGATCAAGCGTTGGGTGTGAAAAAAGATGTCTCTGGAAGCTCGGATTTCCATTCCAAGTCTAGCACATCATGGACTACAACAGTGAAAACAGGAGCAGTAGGGGGAAGAGCATGGGCATATGGTGGTGGTGCTTGGGGAAAAGAAAAAATGTGCATGACTGGTAACTTGCCGCATCCTTGGCGTATGTGGAAGCTTAATAATGTTCATGAAATTTTGAAACGTGATTACCAGCTGCGTCCGGTTGCTATTGAGATATTTAGCATGGATGGGTGTAATGATCTCCTTGTGTTCCACAAGAAAGAGAGGGAAGAAGTTTTCAAAAATCTGGTTGCCATGAATCTTCCAAGGAACAGCATGCTCGACACAACCATTTCAGGATCAGCTAAACAGGAAAGTAACGAGGGAGGCCGGCTTTTCAAATTAATGGCGAAGTCTTTCTCGAAAAGATGGCAAAATGGAGAAATCAGCAATTTCCAATACCTAATGCATCTCAATACCTTAGCAGGACGTGGATACAGTGATCTCACACAGTATCCTGTATTTCCGTGGGTTCTAGCAGATTATGATAGCGAGAGTCTTGATTTTTCAGATCCAAAAACATTCCGCAAGCTTCACAAACCAATGGGTTGCCAGACACCTGAAGGAGAAGAAGAATTTAGAAAACGATATGAGAGCTGGGATGACCCCGAGGTTCCAAAATTTCATTATGGTTCTCACTATTCAAGTGCTGGAATTGTTCTGTTTTACCTTATTCGCCTCCCACCATTCAGTTCTGAAAATCAGAAGCTCCAGGGCGGTCAGTTTGATCATGCTGATAGACTCTTCAATAGTATTAAAGATACTTGGCTAAGTGCAGCAGGAAAGGGAAATACTTCAGACGTGAAAGAACTAATTCCTGAATTCTTCTACATGCCCGAGTTTTTGGAAAATAGATTCAGCCTTGATCTGGGTGAAAAACAGTCAGGAGAGAAGGTTGGTGATGTCTTTTTACCTCCTTGGGCTAGAGGTAGTGTTCGTGAGTTCATCCTCAAACACAGAGAAGCGTTGGAGTCAGACTATGTCTCAGAGAATTTGCATCATTGGATAGATCTCATATTTGGGTACAAACAGAGAGGAAAGGCTGCAGAAGAAGCTGTGAATGTTTTCTATCATTACACATACGAAGGAAATGTTGATATTGATGCAGTTACCGACCCCGCAATGAAAGCTTCTATACTAGCGCAGATTAATCATTTTGGGCAAACTCCTAAACAACTATTCCCGAAAGCTCATGTCAAAAGAAGAACAGACAGAAAAATTCCTCTCCACCCTCTGAAACACTCGATGCATCTAGTTCCTCACGAAATACGTAAATGCTCATCTTCTATAAGCCAGATCATTACTTTCCACGACAAGGTACTCGTTGCTGGAGCCAACTGTTTCCTGAAACCTAGAGGCTATACCAAATACATAACATGGGGATTCCCAGACAGGAGCTTGAGATTTATGAGCTATGATCAGGACAAACTGCTATCAACCCATGAAAATCTCCATGAAAGCAACCAGATTCAGTGTGCTGGTGTAAGTCACGATGGGCGCATTGTGGTCACTGGAGCAGAGGATGGTTTAGTGTGCGTGTGGAGAGTAAGCAAGGATGGTCCACGTGGTTCACGGCGTTTACGGTTAGAGAAAGCCCTATGTGCTCACACAGCTAAAGTCACATGTCTACGTGTAAGCCAACCGTACATGATGATTGCAAGTGGGTCAGACGACTGTACAGTCATCATATGGGATCTCAGTTCATTGAGTTTTGTGAGGCAGCTTCCTGACTTCCCAGTTCCCATTTCAGCAATCTACATAAACGACCTTACTGGGGAAATTGTAACCGCTGCTGGAACTGTCCTTGCGGTTTGGAGCATCAATGGCGATTGCCTTGCTGTGGCTAACACATCGCAGTTACCATCTGATTCGGTATTATCAGTAACAGGCTCAACATCTTCCGACTGGCTTGAGACAAGCTGGTATGTAACTGGTCATCAGAGTGGAGCAGTTAAAGTATGGCGGATGATTCATTGTACTGATCCGGTGAGTGCCGAGAGCAAAACAAGTAGTAGCAACAGAACAGGAGGGCTGAATTTGGGTGATCAAGTGCCAGAATACAAGTTGATTCTACACAAGGTGTTGAAATTCCACAAGCAACCAGTCACCGCGCTCCATCTCACAAGCGACCTGAAGCAGTTACTAAGCGGTGATTCAGCTGGACAGTTACTTTCATGGACAGTACCAGATGAGACATTAAGAGCTTCAATGAAACAAGCTTCATTAAAACAGGCTTCATTAAAACAGGCTTCACTGAAACAGGCTTCATCGGTTTAG
