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经典一抗-alpha Smooth Muscle Actin (3G2) Mouse mAb
Background
Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. Defects in ACTA2 are the cause of aortic aneurysm familial thoracic type 6 (AAT6) [MIM:611788]. They are primarily associated with a characteristic histologic appearance known as 'medial necrosis' or 'Erdheim cystic medial necrosis' in which there is degeneration and fragmentation of elastic fibers, loss of smooth muscle cells, and an accumulation of basophilic ground substance.
Gene Symbol
ACTA2
Alternative Names
ACTA2; ACTSA; ACTVS; GIG46; Actin; aortic smooth muscle; Alpha-actin-2; Cell growth-inhibiting gene 46 protein
Uniprot收起
P62736
Uniprot link
Application
- WB
- IHC
-
Western blot analysis of alpha Smooth Muscle Actin (3G2) in Hela, A549, HL6, U2OS, C6 lysates using alpha Smooth Muscle Actin (3G2) antibody
Western blot analysis of alpha Smooth Muscle Actin (3G2) in αSmooth Muscle Actin in Rat Brain, MCF7, C6 and 3T3 lysates using alpha Smooth Muscle Actin (3G2) antibody
Mol Weight
Calculated MW: 42 kDa; Observed MW: 42 kDa
Source
Mouse
Isotype
IgG1
Clonality
Monoclonal Antibody
Immunogen
Synthetic Peptide of α-SMA
Reactivity
Human,Mouse,Rat
Purification
Affinity Purified
Concentration收起
1 mg/ml
Buffer收起
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide, pH 7.3.
Dilution
WB: 1/500-1/1000 IHC: 1/50-1/100 IF: 1/50-1/200
Storage
Shipped at 4°C. Store at -20°C for one year. Avoid freeze/thaw cycles.