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编号：C33866-100ul
产品名称：CAF1A Conjugated Antibody
种属反应性：Hu
来源种属：Rabbit
克隆性：Polyclonal
规格：100ul
标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750
应用详情：Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000
特异性：The antibody detects endogenous levels of total CAF1A protein.
其他名称：Chromatin assembly factor 1 subunit A;CAF-1 subunit A;Chromatin assembly factor I p150 subunit;CAF-I 150 kDa subunit;CAF-I p150
计算分子量：150
免疫原描述：Synthesized peptide derived from internal of human CAF1A.
标记：Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750
激发/发射波长：AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm
配方：0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
保存：Store at 4˚C in dark for 6 months
背景：Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci By similarity. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
产地：SAB 美国
//品牌：SAB Signalway Antibody/////更多产品欢迎查询我们官网：www.salmart.cn，销售人员QQ：439095771 QQ：996676869 电话：0755-33160345，13006636686
产品名称：CAF1A Conjugated Antibody
种属反应性：Hu
来源种属：Rabbit
克隆性：Polyclonal
规格：100ul
标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750
应用详情：Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000
特异性：The antibody detects endogenous levels of total CAF1A protein.
其他名称：Chromatin assembly factor 1 subunit A;CAF-1 subunit A;Chromatin assembly factor I p150 subunit;CAF-I 150 kDa subunit;CAF-I p150
计算分子量：150
免疫原描述：Synthesized peptide derived from internal of human CAF1A.
标记：Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750
激发/发射波长：AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm
配方：0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
保存：Store at 4˚C in dark for 6 months
背景：Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci By similarity. Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.
产地：SAB 美国
//品牌：SAB Signalway Antibody/////更多产品欢迎查询我们官网：www.salmart.cn，销售人员QQ：439095771 QQ：996676869 电话：0755-33160345，13006636686
