编号：C49648-100ul

产品名称：KMT5A/SETD8/Pr-SET7 Conjugated Antibody

种属反应性：Hu,,Ms

来源种属：Rabbit

克隆性：Monoclonal

规格：100ul

标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

应用详情：Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

特异性：

其他名称：H4 K20 HMTase antibody
H4 K20 specific histone methyltransferase antibody
H4-K20-HMTase SETD8 antibody
Histone H4 K20 methyltransferase antibody
Histone lysine N methyltransferase H4 lysine 20 specific antibody
Histone-lysine N-methyltransferase SETD8 antibody
Lysine N-methyltransferase 5A antibody
N-lysine methyltransferase SETD8 antibody
Pr SET 7 antibody
Pr SET7 antibody
PR-Set7 antibody
PR/SET domain containing protein 07 antibody
PR/SET domain containing protein 8 antibody
PR/SET domain-containing protein 07 antibody
PR/SET07 antibody
PrSET7 antibody
SET 07 antibody
SET 8 antibody
SET domain containing (lysine methyltransferase) 8 antibody
SET domain containing 8 antibody
SET domain containing lysine methyltransferase 8 antibody
SET domain containing protein 8 antibody
SET domain-containing protein 8 antibody
SET07 antibody
SET8 antibody
SETD 8 antibody
setd8 antibody
SETD8_HUMAN antibody


计算分子量：

免疫原描述：Recombinant protein

标记：Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

激发/发射波长：AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

配方：0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存：Store at 4˚C in dark for 6 months

背景：Protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. All monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions , benef playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contribute to the maintenance of proper higher order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53 / TP53 at 'Lys-382', leading to repress p53 / TP53-target genes.

产地：SAB 美国

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