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编号：C48869-100ul
产品名称：Dnmt3a Conjugated Antibody
种属反应性：Hu,,Rt
来源种属：Rabbit
克隆性：Monoclonal
规格：100ul
标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750
应用详情：Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000
特异性：
其他名称：DNA (cytosine 5) methyltransferase 3 alpha antibody DNA (cytosine 5) methyltransferase 3A antibody DNA (cytosine-5)-methyltransferase 3A antibody DNA cytosine methyltransferase 3A2 antibody DNA methyltransferase 3 alpha antibody DNA methyltransferase 3a antibody DNA methyltransferase HsaIIIA antibody DNA MTase HsaIIIA antibody DNM3A_HUMAN antibody DNMT 3a antibody DNMT antibody Dnmt3a antibody DNMT3A2 antibody M.HsaIIIA antibody MCMT antibody OTTHUMP00000201149 antibody TBRS antibody
计算分子量：120 kDa
免疫原描述：recombinant protein
标记：Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750
激发/发射波长：AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm
配方：0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
保存：Store at 4˚C in dark for 6 months
背景：Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, and this methylation results in transcriptional repression of the target gene. The Dnmt enzymes are encoded by independent genes. Dnmt1 is the most abundant, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development. Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3. Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, is expressed at substantially lower levels in adult tissues, and is likely involved in methylating newly integrated retroviral DNA. Dnmt3a and Dnmt3b are encoded by two distinct genes, but both are abundantly expressed in embryonic stem cells, where they also methylate CpG motifs on DNA.
产地：SAB 美国
//品牌：SAB Signalway Antibody/////更多产品欢迎查询我们官网：www.salmart.cn，销售人员QQ：439095771 QQ：996676869 电话：0755-33160345，13006636686
产品名称：Dnmt3a Conjugated Antibody
种属反应性：Hu,,Rt
来源种属：Rabbit
克隆性：Monoclonal
规格：100ul
标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750
应用详情：Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000
特异性：
其他名称：DNA (cytosine 5) methyltransferase 3 alpha antibody DNA (cytosine 5) methyltransferase 3A antibody DNA (cytosine-5)-methyltransferase 3A antibody DNA cytosine methyltransferase 3A2 antibody DNA methyltransferase 3 alpha antibody DNA methyltransferase 3a antibody DNA methyltransferase HsaIIIA antibody DNA MTase HsaIIIA antibody DNM3A_HUMAN antibody DNMT 3a antibody DNMT antibody Dnmt3a antibody DNMT3A2 antibody M.HsaIIIA antibody MCMT antibody OTTHUMP00000201149 antibody TBRS antibody
计算分子量：120 kDa
免疫原描述：recombinant protein
标记：Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750
激发/发射波长：AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm
配方：0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
保存：Store at 4˚C in dark for 6 months
背景：Methylation at the 5'-position of cytosine is the only known naturally occurring covalent modification of the mammalian genome. DNA methylation requires the enzymatic activity of DNA 5-cytosine methyltransferase (Dnmt) proteins, which catalyze the transfer of a methyl group from S-adenosyl methionine to the 5'-position of cytosines residing in the dinucleotide CpG motif, and this methylation results in transcriptional repression of the target gene. The Dnmt enzymes are encoded by independent genes. Dnmt1 is the most abundant, and it preferentially methylates hemimethylated DNA and coordinates gene expression during development. Additional mammalian Dnmt proteins include Dnmt2 and Dnmt3. Dnmt2 lacks the large N-terminal regulator domain of Dnmt1, is expressed at substantially lower levels in adult tissues, and is likely involved in methylating newly integrated retroviral DNA. Dnmt3a and Dnmt3b are encoded by two distinct genes, but both are abundantly expressed in embryonic stem cells, where they also methylate CpG motifs on DNA.
产地：SAB 美国
//品牌：SAB Signalway Antibody/////更多产品欢迎查询我们官网：www.salmart.cn，销售人员QQ：439095771 QQ：996676869 电话：0755-33160345，13006636686
