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Cyclin A1+ Cyclin A2 Conjugated Antibody
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  • 货号 Cyclin A1+ Cyclin A2 Conj
  • 品牌 Signalway Antibody LLC(SAB) ( 一级代理 )
  • CAS号
  • 规格/包装 100ul 来源:兔子单克隆 AF标记抗
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编号:C49194-100ul

产品名称:Cyclin A1+ Cyclin A2 Conjugated Antibody

种属反应性:Hu

来源种属:Rabbit

克隆性:Monoclonal

规格:100ul

标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

应用详情:Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

特异性:

其他名称:CCN1 antibody
CCNA antibody
CCNA1 antibody
CCNA2 antibody
CT146 antibody
Cyclin-A antibody
Cyclin-A1 antibody
Cyclin-A2 antibody


计算分子量:52/49 kDa

免疫原描述:recombinant protein

标记:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

激发/发射波长:AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

配方:0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存:Store at 4˚C in dark for 6 months

背景:The critical role that the family of regulatory proteins known as cyclins play in eukaryotic cell cycle regulation is well established. Cyclin A accumulates prior to cyclin B in the cell cycle, appears to be involved in control of S phase and has been shown to associate with cyclin-dependent kinase-2 (Cdk2). In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcription factors DRTF1 and E2F, and retinoblastoma protein p110. A second form of cyclin A, named cyclin A1 because of its high sequence homology to Xenopus cyclin A1, is most highly expressed in germ cells. It has been proposed that cyclin A1 can associate with Cdk2, p39 and Cdc2 p34. Cyclin A2 is a member of the highly conserved cyclin family. Cyclins regulate CDK kinases and different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. Cyclin A2 is expressed in all tissues tested, in contrast to cyclin A1, which is present only in germ cells. The Cyclin A2 protein binds and activates CDC2 or CDK2 kinases, and thus promotes both cell cycle G1/S and G2/M transitions. Cyclin A2 also functions in the transition to DNA replication and synthesis phases of the cell cycle and is quickly destroyed as the cell moves into mitosis.

产地:SAB 美国

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