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PI 3 Kinase Class 3 Conjugated Antibody
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  • 货号 PI 3 Kinase Class 3 Conju
  • 品牌 Signalway Antibody LLC(SAB) ( 一级代理 )
  • CAS号
  • 规格/包装 100ul 来源:兔子单克隆 AF标记抗
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编号:C48800-100ul

产品名称:PI 3 Kinase Class 3 Conjugated Antibody

种属反应性:Hu,,Ms,,Rt

来源种属:Rabbit

克隆性:Monoclonal

规格:100ul

标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

应用详情:Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

特异性:

其他名称:hVps34 antibody
MGC61518 antibody
Phosphatidylinositol 3 kinase catalytic subunit type 3 antibody
Phosphatidylinositol 3 kinase class 3 antibody
Phosphatidylinositol 3 kinase p100 subunit antibody
Phosphatidylinositol 3-kinase catalytic subunit type 3 antibody
Phosphatidylinositol 3-kinase p100 subunit antibody
Phosphoinositide 3 kinase class 3 antibody
Phosphoinositide-3-kinase class 3 antibody
PI3 kinase type 3 antibody
PI3-kinase type 3 antibody
PI3K type 3 antibody
Pik3c3 antibody
PK3C3_HUMAN antibody
PtdIns 3 kinase type 3 antibody
PtdIns-3-kinase type 3 antibody
Vps 34 antibody
Vps34 antibody


计算分子量:100 kDa

免疫原描述:recombinant protein

标记:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

激发/发射波长:AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

配方:0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存:Store at 4˚C in dark for 6 months

背景:Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the 3' OH position of the inositol ring of inositol lipids. PI 3-kinase p100 (phosphoinositide-3-kinase p100 subunit), also known as hVps34 or PIK3C3 (phosphoinositide-3-kinase, class III), is a member of the PI3/PI4-kinase family. It is ubiquitously expressed with predominant expression in skeletal muscle and is believed to participate in endosome to lysosome transport, multivesicular body formation, autophagy and retrograde endosome to Golgi transport. PI 3-kinase p100 is the catalytic subunit of class III PI3Ks and forms a heterodimer with p150, a regulatory subunit of class 3 PI3Ks. PI 3-kinase p100 exclusively phosphorylates phosphatidylinositol to produce PtdIns3P. Unlike class I PI3Ks, whose activities are enhanced in the presence of magnesium, PI 3-kinase p100 activity is enhanced by manganese. Its activity can also be regulated by nutrients, suggesting an important role of PI-3 kinase p100 in the regulation of mTOR protein synthesis and autophagy.

产地:SAB 美国

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