编号：C48454-100ul

产品名称：NKX3A Conjugated Antibody

种属反应性：Hu

来源种属：Mouse

克隆性：Monoclonal

规格：100ul

标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

应用详情：Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

特异性：

其他名称：BAPX 2 antibody
BAPX2 antibody
Homeobox protein NK-3 homolog A antibody
Homeobox protein Nkx 3.1 antibody
Homeobox protein Nkx-3.1 antibody
Homeobox protein Nkx3.1 antibody
NK homeobox (Drosophila) family 3 A antibody
NK homeobox family 3 A antibody
NK homeobox, family 3, member A antibody
NK3 homeobox 1 antibody
NK3 transcription factor homolog A antibody
NK3 transcription factor related locus 1 antibody
NKX 3 antibody
Nkx 3.1 antibody
NKX 3A antibody
NKX3 1 antibody
NKX3 antibody
Nkx3-1 antibody
NKX3.1 antibody
Nkx3.1, mouse, homolog of antibody
NKX31_HUMAN antibody
NKX3A antibody


计算分子量：26 kDa

免疫原描述：Recombinant protein

标记：Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

激发/发射波长：AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

配方：0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存：Store at 4˚C in dark for 6 months

背景：The homeobox gene Nkx-3.1 is the human homolog of Drosophila bagpipe, which, in conjunction with tinman, determines cell fate in the dorsal mesoderm. In mammalian species, Nkx-3.1 is predominantly expressed in prostate, and it regulates prostate development in response to sonic hedgehog (Shh) signaling by exerting growth-suppressive and differentiating effects on prostatic epithelium. Nkx-3.1 is also expressed at lower levels in other tissues, including the heart and gut, in a Shh independent manner, where it plays a role in regulating proliferation of glandular epithelium and in the formation of ducts in prostate and minor salivary glands. Nkx-3.1 preferentially binds the TAAGTA sequence, which has not been reported for any other NK class homeoprotein. The human Nkx-3.1 gene is located on chromosome 8q21, which frequently undergoes a loss of heterozygosity, and although Nkx-3.1 is not a tumor suppressor gene, it may be a useful marker for benign and malignant prostate epithelium.

产地：SAB 美国

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