编号：C48411-100ul

产品名称：KDM3A Conjugated Antibody

种属反应性：Hu

来源种属：Mouse

克隆性：Monoclonal

规格：100ul

标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

应用详情：Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

特异性：

其他名称：DKFZp686A24246 antibody
DKFZp686P07111 antibody
JHDM2A antibody
JHMD2A antibody
JmjC domain-containing histone demethylation protein 2A antibody
JMJD1 antibody
JMJD1A antibody
Jumonji C domain containing histone demethylase 2A antibody
Jumonji domain containing 1 antibody
Jumonji domain containing 1A antibody
Jumonji domain containing protein 1A antibody
Jumonji domain-containing protein 1A antibody
Kdm3a antibody
KDM3A_HUMAN antibody
KIAA0742 antibody
Lysine (K) specific demethylase 3A antibody
Lysine-specific demethylase 3A antibody
Testis specific protein A antibody
TSGA antibody


计算分子量：147 kDa

免疫原描述：Recombinant protein

标记：Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

激发/发射波长：AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

配方：0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存：Store at 4˚C in dark for 6 months

背景：JMJD1A (Jumonji domain containing 1A), also known as TSGA (testis-specific protein A), JMJD1, KDM3A, JHDM2A (JMJC domain-containing histone demethylation protein 2A) or JHMD2A, is a member of the JHDM2 histone demethylase family of proteins that is predominantly expressed in testis. Containing one JMJC domain and a C-terminal C2HC4 zinc finger, JMJD1A functions as a mono- and dimethylation-specific demethylase, binding iron and a-ketoglutarate as cofactors and demethylating Lysine 9 of Histone H3. This suggests that JMJD1A plays a central role in the histone code and participates in nuclear hormone receptor-based transcriptional regulation. In addition, JMJD1A plays an important role in the regulation of cell growth during development and in chromatin regulation. JMJD1A directly regulates the expression of TNP1 and Protamine 1 (proteins required for the proper packaging and condensation of sperm chromatin) and, therefore, plays an essential role in spermatogenesis.

产地：SAB 美国

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