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NFKBIE Conjugated Antibody
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  • 货号 NFKBIE Conjugated Antibod
  • 品牌 Signalway Antibody LLC(SAB) ( 一级代理 )
  • CAS号
  • 规格/包装 100ul 来源:兔子多克隆 AF标记抗
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  • 储存条件
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编号:C35589-100ul

产品名称:NFKBIE Conjugated Antibody

种属反应性:Hu

来源种属:Rabbit

克隆性:Polyclonal

规格:100ul

标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

应用详情:Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

特异性:The antibody detects endogenous levels of total NFKBIE protein.

其他名称:IKBE

计算分子量:45

免疫原描述:Fusion protein corresponding to a region derived from internal residues of human Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon

标记:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

激发/发射波长:AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

配方:0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存:Store at 4˚Cin dark for 6 months

背景:The protein encoded by this gene binds to components of NF-kappa-B, trapping the complex in the cytoplasm and preventing it from activating genes in the nucleus. Phosphorylation of the encoded protein targets it for destruction by the ubiquitin pathway, which activates NF-kappa-B by making it available to translocate to the nucleus. NFKBIE protein expression is up-regulated following NF-B activation and during myelopoiesis. NFKBIE is able to inhibit NF-B-directed transactivation via cytoplasmic retention of REL proteins. NFKB1 or NFKB2 is bound to REL, RELA, or RELB to form the NF-B transcription factor complex. The NF-B complex is inhibited by I-kappa-B proteins (NFKBIA or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm.

产地:SAB 美国

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