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ALOX5 Conjugated Antibody
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  • 货号 ALOX5 Conjugated Antibody
  • 品牌 Signalway Antibody LLC(SAB) ( 一级代理 )
  • CAS号
  • 规格/包装 100ul 来源:兔子多克隆 AF标记抗
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编号:C35564-100ul

产品名称:ALOX5 Conjugated Antibody

种属反应性:Hu

来源种属:Rabbit

克隆性:Polyclonal

规格:100ul

标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

应用详情:Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000

特异性:The antibody detects endogenous levels of total ALOX5 protein.

其他名称:5-LO, 5LPG, LOG5, 5-LOX

计算分子量:

免疫原描述:Fusion protein corresponding to a region derived from internal residues of human Arachidonate 5-lipoxygenase

标记:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750

激发/发射波长:AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm

配方:0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide

保存:Store at 4˚C in dark for 6 months

背景:This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

产地:SAB 美国

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