
商家描述
商家资质信息
产品评价(0)
编号:C48816-100ul
产品名称:FOXO1A Conjugated Antibody
种属反应性:Hu,,Ms,,Rt,,zebrafish
来源种属:Rabbit
克隆性:Monoclonal
规格:100ul
标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750
应用详情:Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000
特异性:
其他名称:FKH 1 antibody FKH1 antibody FKHR antibody Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma) antibody Forkhead box O1 antibody Forkhead box protein O1 antibody Forkhead box protein O1A antibody Forkhead in rhabdomyosarcoma antibody Forkhead, Drosophila, homolog of, in rhabdomyosarcoma antibody FoxO transcription factor antibody foxo1 antibody FOXO1_HUMAN antibody FOXO1A antibody OTTHUMP00000018301 antibody
计算分子量:80 kDa
免疫原描述:recombinant protein
标记:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750
激发/发射波长:AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm
配方:0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
保存:Store at 4˚C in dark for 6 months
背景:FKHR (for forkhead in rhabdomyosarcoma) and FKHRL1 are members of the forkhead family of transcription factors. Transcriptional activation of FKHR proteins is regulated by the serine/threonine kinase Akt1, which phosphorylates FKHRL1 and results in FKHRL1 associating with 14-3-3 proteins and being retained in the cytoplasm. Induction of apoptosis or withdrawal of growth factors stimulates dephosphorylation and nuclear translocation of FKHR proteins, leading to FKHR-induced gene-specific transcriptional activation. FKHR, also designated forkhead box protein O1A (FOXO1), is a ubiquitously expressed protein that shuttles between the cytoplasm and nucleus. Genetic mutations in FKHR genes, including the t(2;13) and t(1;3) translocations, are commonly found in alveolar rhabdomyosarcomas. These translocations result in the fusion of the amino terminus of Pax-3 or Pax-7, including the paired box and homeodomain DNA-binding domains, with the carboxy-terminus of FKHR, which contains a transcriptional activation domain. The Pax-3/FKHR fusion protein appears to function as an oncogenic transcription factor that enhances the activation of normal Pax-3 target genes.
产地:SAB 美国
//品牌:SAB Signalway Antibody/////更多产品欢迎查询我们官网:www.salmart.cn,销售人员QQ:439095771 QQ:996676869 电话:0755-33160345,13006636686
产品名称:FOXO1A Conjugated Antibody
种属反应性:Hu,,Ms,,Rt,,zebrafish
来源种属:Rabbit
克隆性:Monoclonal
规格:100ul
标记物:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750
应用详情:Suggested Dilution:
AF350 conjugated: most applications: 1: 50 - 1: 250
AF405 conjugated: most applications: 1: 50 - 1: 250
AF488 conjugated: most applications: 1: 50 - 1: 250
AF555 conjugated: most applications: 1: 50 - 1: 250
AF594 conjugated: most applications: 1: 50 - 1: 250
AF647 conjugated: most applications: 1: 50 - 1: 250
AF680 conjugated: most applications: 1: 50 - 1: 250
AF750 conjugated: most applications: 1: 50 - 1: 250
Biotin conjugated: working with enzyme-conjugated streptavidin, most applications: 1: 50 - 1: 1,000
特异性:
其他名称:FKH 1 antibody FKH1 antibody FKHR antibody Forkhead (Drosophila) homolog 1 (rhabdomyosarcoma) antibody Forkhead box O1 antibody Forkhead box protein O1 antibody Forkhead box protein O1A antibody Forkhead in rhabdomyosarcoma antibody Forkhead, Drosophila, homolog of, in rhabdomyosarcoma antibody FoxO transcription factor antibody foxo1 antibody FOXO1_HUMAN antibody FOXO1A antibody OTTHUMP00000018301 antibody
计算分子量:80 kDa
免疫原描述:recombinant protein
标记:Biotin,AF350,AF405,AF488,AF555,AF594,AF647,AF680,AF750
激发/发射波长:AF350: 346nm/442nm
AF405: 401nm/421nm
AF488: 493nm/519nm
AF555: 555nm/565nm
AF594: 591nm/614nm
AF647: 651nm/667nm
AF680: 679nm/702nm
AF750: 749nm/775nm
配方:0.01M Sodium Phosphate, 0.25M NaCl, pH 7.6, 5mg/ml Bovine Serum Albumin, 0.02% Sodium Azide
保存:Store at 4˚C in dark for 6 months
背景:FKHR (for forkhead in rhabdomyosarcoma) and FKHRL1 are members of the forkhead family of transcription factors. Transcriptional activation of FKHR proteins is regulated by the serine/threonine kinase Akt1, which phosphorylates FKHRL1 and results in FKHRL1 associating with 14-3-3 proteins and being retained in the cytoplasm. Induction of apoptosis or withdrawal of growth factors stimulates dephosphorylation and nuclear translocation of FKHR proteins, leading to FKHR-induced gene-specific transcriptional activation. FKHR, also designated forkhead box protein O1A (FOXO1), is a ubiquitously expressed protein that shuttles between the cytoplasm and nucleus. Genetic mutations in FKHR genes, including the t(2;13) and t(1;3) translocations, are commonly found in alveolar rhabdomyosarcomas. These translocations result in the fusion of the amino terminus of Pax-3 or Pax-7, including the paired box and homeodomain DNA-binding domains, with the carboxy-terminus of FKHR, which contains a transcriptional activation domain. The Pax-3/FKHR fusion protein appears to function as an oncogenic transcription factor that enhances the activation of normal Pax-3 target genes.
产地:SAB 美国
//品牌:SAB Signalway Antibody/////更多产品欢迎查询我们官网:www.salmart.cn,销售人员QQ:439095771 QQ:996676869 电话:0755-33160345,13006636686