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一般描述
The inhibitory neurotransmitter, GABA, acts through two ligand-gated channels, GABA(A) and GABA© receptors and GABA(B), the latter of which acts through a G protein mechanism. GABA(B)R2 is one of the two G-protein coupled receptors for GABA(B) that acts as a heteromeric assembly with GABA(B)R1.
特异性
GABAB Receptor R2 subunit, N-terminus. No reactivity with GABABR1 has been detected.
免疫原
Epitope: a.a. 42-54 rat
peptide residues 42-54 of the rat 105 kDa GABA(b)R2 protein
应用
Immunoblotting: 1:500-1:1,000. Membrane preparations with proteinase inhibitors are recommended. Whole rat brain membrane preparations. The antibody detects a ~105kDa band under standard western conditions. The immunogen used is 100% conserved in human by sequence analysis; other species have not been examined for reactivity or homology.
Optimal working dilutions must be determined by end user.
This Anti-GABA B Receptor R2 Antibody, a.a. 42-54 rat is validated for use in WB for the detection of GABA B Receptor R2.
Research Category
Neuroscience
Research Sub Category
Neurotransmitters & Receptors
外形
Purified immunoglobulin. Liquid. Buffer = PBS containing 0.02% sodium azide.
Format: Purified
储存及稳定性
Maintain frozen at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.
其他说明
Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.