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Calcineurin A Antibody
  • 商城价格 登录后可查看价格
  • 货号 LBP82080
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 100 μg
  • 单位 个
  • 储存条件 见详情介绍
  • 现货状态
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品牌：

Leading Biology

货号：

LBP82080

规格：

100 μg

产品官网链接：

产品分类：

多克隆抗体

研究领域：

产品概述：

Calcineurin is a calcium/calmodulin-dependent serine/threonine protein phosphatase. The active enzyme is a heterodimer consisting of a catalytic A subunit of 61 kDa and a myristylated regulatory B subunit of 19 kDa that binds calcium. The catalytic A subunit consists of an amino terminal catalytic domain, followed by calmodulin and B subunit binding sites, and a caboxyl-terminal autoinhibitory domain. Calnineurin is the target of immunosuppressant dr μgs such as cyclosporin A and FK506. Calcineurin controls the translocation of nuclear factors of activated T cells (NFAT), a family of transcriptional activators that control the expression of cytokine genes essential to immune response, from the cytosol into the nucleus of activated T cells. Calcineurin has been proposed to play an important role in mediating calcium-activated cell death.

来源：

Rabbit

靶点/蛋白质：

Calcineurin A

特异性：

Human, Mouse, Rat, Rabbit, Hamster, Bovine

存储温度：

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

存储溶液：

应用：

参考文献：

详情介绍：

Function Calcium-dependent, calmodulin-stimulated protein phosphatase. This subunit may have a role in the calmodulin activation of calcineurin.

别名：

PPP3CA, CCN1, CNA1, CALN, CALNA, CALNA1, PPP2B

说明书：

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