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APOA1 / Apolipoprotein A 1 Antibody
  • 商城价格 登录后可查看价格
  • 货号 LBP71882
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 50 μg
  • 单位 个
  • 储存条件 见详情介绍
  • 现货状态
  • 数量

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品牌：

Leading Biology

货号：

LBP71882

规格：

50 μg

产品官网链接：

产品分类：

多克隆抗体

研究领域：

产品概述：

Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.

来源：

Goat

靶点/蛋白质：

Recognizes human Apolipoprotein A-I; minimum cross-reactivity against Type A-II, B, C-I, C-II, C-III, E and J Apolipoproteins and other human serum proteins.

特异性：

Human

存储温度：

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

存储溶液：

应用：

ELISA (1:5000-1:10000), IHC-P (5 μg/ml), WB (1:2500-1:5000)

参考文献：

Shoulders C.C.,et al.Nucleic Acids Res. 11:2827-2837(1983). Cheung P.,et al.Nucleic Acids Res. 11:3703-3715(1983). Karathanasis S.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:6147-6151(1983). Seilhamer J.J.,et al.DNA 3:309-317(1984). Sharpe C.R.,et al.Nucleic Acids Res. 12:3917-3932(1984).

详情介绍：

Function Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. Cellular_Location Secreted. Tissue_Location Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease.

别名：

Apolipoprotein A-I, Apo-AI, ApoA-I, Apolipoprotein A1, Proapolipoprotein A-I, ProapoA-I, Truncated apolipoprotein A-I, Apolipoprotein A-I(1-242), APOA1

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