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ACD antibody - C-terminal region
  • 商城价格 登录后可查看价格
  • 货号 LBP65613
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 50 μg
  • 单位 个
  • 储存条件 见详情介绍
  • 现货状态
  • 数量

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品牌：

Leading Biology

货号：

LBP65613

规格：

50 μg

产品官网链接：

产品分类：

多克隆抗体

研究领域：

产品概述：

来源：

Rabbit

靶点/蛋白质：

特异性：

Human

存储温度：

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

存储溶液：

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

应用：

参考文献：

Liu D.,et al.Nat. Cell Biol. 6:673-680(2004). Ota T.,et al.Nat. Genet. 36:40-45(2004). Martin J.,et al.Nature 432:988-994(2004). Keegan C.E.,et al.Hum. Mol. Genet. 14:113-123(2005). Ye J.Z.-S.,et al.Genes Dev. 18:1649-1654(2004).

详情介绍：

Function Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Promotes binding of POT1 to single-stranded telomeric DNA. Modulates the inhibitory effects of POT1 on telomere elongation. The ACD-POT1 heterodimer enhances telomere elongation by increasing telomerase processivity. Plays a role in shelterin complex assembly. May play a role in organogenesis. Cellular_Location Nucleus. Chromosome, telomere

别名：

Adrenocortical dysplasia protein homolog, POT1 and TIN2-interacting protein, ACD, PIP1, PTOP, TINT1, TPP1

说明书：

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