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RARG / RAR-Gamma Antibody
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  • 货号 LBP63174
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 50 μl
  • 单位 个
  • 储存条件 见详情介绍
  • 现货状态
  • 数量

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品牌：

Leading Biology

货号：

LBP63174

规格：

50 μl

产品官网链接：

产品分类：

多克隆抗体

研究领域：

产品概述：

Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function (By similarity).

来源：

Rabbit

靶点/蛋白质：

Human, mouse RARG

特异性：

Human, Mouse

存储温度：

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

存储溶液：

应用：

IHC-P (7.5 μg/ml), WB (1:500-1:3000),

参考文献：

Krust A.,et al.Proc. Natl. Acad. Sci. U.S.A. 86:5310-5314(1989). Ishikawa T.,et al.Mol. Endocrinol. 4:837-844(1990). Lehmann J.M.,et al.Nucleic Acids Res. 19:573-578(1991). Ota T.,et al.Nat. Genet. 36:40-45(2004). Scherer S.E.,et al.Nature 440:346-351(2006).

详情介绍：

Function Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function (By similarity). Cellular_Location Nucleus.

别名：

Retinoic acid receptor gamma, RAR-gamma, Nuclear receptor subfamily 1 group B member 3, RARG, NR1B3

说明书：

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