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PTCH (C Terminus) Antibody (C-Term)
  • 商城价格 登录后可查看价格
  • 货号 LBP63114
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 0.1 mg
  • 单位 个
  • 储存条件 见详情介绍
  • 现货状态
  • 数量

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品牌：

Leading Biology

货号：

LBP63114

规格：

0.1 mg

产品官网链接：

产品分类：

多克隆抗体

研究领域：

产品概述：

This antibody is expected to recognise all reported isoforms. Variants (NP_001077073.1; NP_001077074.1; NP_001077075.1; NP_001077076.1) encode the same isoform.

来源：

Goat

靶点/蛋白质：

特异性：

Human

存储温度：

Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

存储溶液：

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

应用：

参考文献：

Detecting tissue-specific alternative splicing and disease-associated aberrant splicing of the PTCH gene with exon junction microarrays. Nagao K, Togawa N, Fujii K, Uchikawa H, Kohno Y, Yamada M, Miyashita T. Hum Mol Genet. 2005 Oct 3; [Epub ahead of print] PMID: 16203740

详情介绍：

Function Acts as a receptor for sonic hedgehog (SHH), indian hedgehog (IHH) and desert hedgehog (DHH). Associates with the smoothened protein (SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis. Cellular_Location Membrane; Multi-pass membrane protein. Tissue_Location In the adult, expressed in brain, lung, liver, heart, placenta, skeletal muscle, pancreas and kidney. Expressed in tumor cells but not in normal skin

别名：

Protein patched homolog 1, PTC, PTC1, PTCH1, PTCH

说明书：

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