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Phospho-IRS (Ser616) Antibody (Clone HIR-B1)
  • 商城价格 登录后可查看价格
  • 货号 LM17551
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 100 μg
  • 单位 个
  • 储存条件 见详情介绍
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品牌：

Leading Biology

货号：

LM17551

规格：

100 μg

产品官网链接：

产品分类：

单克隆抗体

研究领域：

产品概述：

Insulin receptor substrates (IRS) subtypes are responsible for several insulin related activities, such as glucose homeostasis, cell growth, cell transformation, apoptosis and insulin signal transduction. The balance between Ser/Thr phosphorylation of IRS has been demonstrated to be an important regulator of insulin signaling. IRS1 has also been shown to be constitutively activated in cancers such as breast cancer, Wilm’s tumors, and adrenal cortical carcinomas. Does not recognize IRS peptide NOT phosphorylated at Ser616 and will not recognize IRS peptide phosphorylated at Tyr183. Also does not react with riboflavin carrier protein which is known to have multiple phosphate groups.

来源：

Mouse

靶点/蛋白质：

Phospho-IRS

特异性：

Human

存储温度：

存储溶液：

应用：

参考文献：

详情介绍：

Function May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).

别名：

IRS, phospho-IRS, Phospho-IRS (Ser616)

说明书：

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