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品牌: | Leading Biology | 货号: | LM17544 |
规格: | 100 μl | 产品官网链接: | |
产品分类: | 单克隆抗体 | 研究领域: | |
产品概述: | 来源: | Mouse | |
靶点/蛋白质: | 特异性: | Human | |
存储温度: | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | 存储溶液: | |
应用: | WB~~1/500 - 1/2000 | 参考文献: | 1. Cancer Sci. 2006 Dec;97(12):1308. 2. Mol Endocrinol. 2006 Nov;20(11):2656-70. 3. Mol Endocrinol. 2007 Jan;21(1):106-25. 4. J Clin Endocrinol Metab. 2007 Nov;92(11):4459-66. |
详情介绍: | Function The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Progesterone receptor isoform B (PRB) is involved activation of c-SRC/MAPK signaling on hormone stimulation. Isoform 4: Increases mitochondrial membrane potential and cellular respiration upon stimulation by progesterone. Cellular_Location Nucleus. Cytoplasm. Note=Nucleoplasmic shuttling is both homone- and cell cycle-dependent. On hormone stimulation, retained in the cytoplasm in the G(1) and G(2)/M phases Isoform 4: Mitochondrion outer membrane | ||
别名: | Progesterone receptor, PR, Nuclear receptor subfamily 3 group C member 3, PGR, NR3C3 | 说明书: |