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PHAP1 / ANP32A Antibody (clone 2G11-4A5)
  • 商城价格 登录后可查看价格
  • 货号 LM17539
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 50 μg
  • 单位 个
  • 储存条件 见详情介绍
  • 现货状态
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品牌：

Leading Biology

货号：

LM17539

规格：

50 μg

产品官网链接：

产品分类：

单克隆抗体

研究领域：

产品概述：

Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1- mediated transcriptional repression.

来源：

Mouse

靶点/蛋白质：

Human PHAP1

特异性：

Human

存储温度：

存储溶液：

应用：

IF (10 μg/ml), IHC-P (5 μg/ml), WB (1:500-1:1000)

参考文献：

Vaesen M.,et al.Biol. Chem. Hoppe-Seyler 375:113-126(1994). Li M.,et al.Biochemistry 35:6998-7002(1996). Chen T.-H.,et al.Mol. Biol. Cell 7:2045-2056(1996). Matilla A.,et al.Nature 389:974-978(1997). Ota T.,et al.Nat. Genet. 36:40-45(2004).

详情介绍：

Function Implicated in a number of cellular processes, including proliferation, differentiation, caspase-dependent and caspase- independent apoptosis, suppression of transformation (tumor suppressor), inhibition of protein phosphatase 2A, regulation of mRNA trafficking and stability in association with ELAVL1, and inhibition of acetyltransferases as part of the INHAT (inhibitor of histone acetyltransferases) complex. Plays a role in E4F1- mediated transcriptional repression. Cellular_Location Nucleus. Cytoplasm. Endoplasmic reticulum. Note=Translocates to the cytoplasm during the process of neuritogenesis (By similarity). Shuttles between nucleus and cytoplasm. Tissue_Location Expressed in all tissues tested. Highly expressed in kidney and skeletal muscle, moderate levels of expression in brain, placenta and pancreas, and weakly expressed in lung. Found in all regions of the brain examined (amygdala, caudate nucleus, corpus callosum, hippocampus and thalamus), with highest levels in amygdala.

别名：

Acidic leucine-rich nuclear phosphoprotein 32 family member A, Acidic nuclear phosphoprotein pp32, pp32, Leucine-rich acidic nuclear protein, LANP, Mapmodulin, Potent heat-stable protein phosphatase 2A inhibitor I1PP2A, Putative HLA-DR-associated protein I, PHAPI, ANP32A, C15orf1, LANP, MAPM, PHAP1

说明书：

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