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Peroxiredoxin III Antibody (12B)
  • 商城价格 登录后可查看价格
  • 货号 LM17530
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 100 μl
  • 单位
  • 储存条件 见详情介绍
  • 现货状态

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品牌:

Leading Biology

货号:

LM17530

规格:

100 μl

产品官网链接:

产品分类:

单克隆抗体

研究领域:

产品概述:

Peroxiredoxin (Prx) is a growing peroxidase family, whose mammalian members have been known to connect with cell proliferation, differentiation, and apoptosis. Many isoforms (about 50 proteins), collected in accordance to the amino acid sequence homology, particularly amino-terminal region containing active site cysteine residue, and the thiol-specific antioxidant activity, distribute throughout all the kingdoms. Among them, mammalian Prx consists of 6 different members grouped into typical 2-Cys, atypical 2-Cys Prx, and 1-Cys Prx. Except Prx VI belonging to 1-Cys Prx subgroup, the other five 2-Cys Prx isotypes have the thioredoxin-dependent peroxidase (TPx) activity utilizing thioredoxin, thioredoxin reductase, and NADPH as a reducing system. Mammalian Prxs are 20 – 30 kDa in molecular size and vary in subcellular localization: Prx I, II, and VI in cytosol, Prx III in mitochondria, Prx IV in ER and secretion, Prx V showing complicated distribution including peroxisome, mitochondria and cytosol. Prx III is involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical-generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol.

来源:

Mouse

靶点/蛋白质:

Peroxiredoxin III

特异性:

Human, Mouse

存储温度:

存储溶液:

应用:

参考文献:

详情介绍:

Function Involved in redox regulation of the cell. Protects radical-sensitive enzymes from oxidative damage by a radical- generating system. Acts synergistically with MAP3K13 to regulate the activation of NF-kappa-B in the cytosol. Cellular_Location Mitochondrion.

别名:

Thioredoxin-dependent peroxide Reductase, mitochondrial, PRDX3, PRX III, Antioxidant protein 1 (AOP-1)

说明书:

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