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品牌: | Leading Biology | 货号: | LM17500 |
规格: | 100 μl | 产品官网链接: | |
产品分类: | 单克隆抗体 | 研究领域: | |
产品概述: | 来源: | Mouse | |
靶点/蛋白质: | 特异性: | Human | |
存储温度: | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | 存储溶液: | |
应用: | WB~~1/500 - 1/2000 FC~~1/200 - 1/400 | 参考文献: | 1.Invest Ophthalmol Vis Sci. 2009 Jun;50(6):2581-90. 2.J Biol Chem. 2009 Oct 2;284(40):27524-32. 3.J Biol Chem. 2010 Jan 22;285(4):2527-36. |
详情介绍: | Function Transcription factor with important functions in the development of the eye, nose, central nervous system and pancreas. Required for the differentiation of pancreatic islet alpha cells (By similarity). Competes with PAX4 in binding to a common element in the glucagon, insulin and somatostatin promoters. Regulates specification of the ventral neuron subtypes by establishing the correct progenitor domains (By similarity). Isoform 5a appears to function as a molecular switch that specifies target genes. Cellular_Location Nucleus. Tissue_Location Fetal eye, brain, spinal cord and olfactory epithelium. Isoform 5a is less abundant than the PAX6 shorter form | ||
别名: | Paired box protein Pax-6, Aniridia type II protein, Oculorhombin, PAX6, AN2 | 说明书: |