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品牌: | Leading Biology | 货号: | LM17488 |
规格: | 100 μl | 产品官网链接: | |
产品分类: | 单克隆抗体 | 研究领域: | |
产品概述: | 来源: | Mouse | |
靶点/蛋白质: | 特异性: | Human | |
存储温度: | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | 存储溶液: | |
应用: | WB~~1/500 - 1/2000 IHC~~1:200~~1000 IF~~1:200~1000. | 参考文献: | 1. J Alzheimers Dis. 2001 Apr;3(2):181-190. 2. Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. 3. Nature. 2003 May 29;423(6939):537-41. |
详情介绍: | Function Required for the control of apoptosis during postnatal growth. Essential for proteolytic processing of an antiapoptotic form of OPA1 which prevents the release of mitochondrial cytochrome c in response to intrinsic apoptoptic signals (By similarity). Promotes changes in mitochondria morphology regulated by phosphorylation of P-beta domain. Cellular_Location Mitochondrion inner membrane; Multi-pass membrane protein | ||
别名: | Presenilins-associated rhomboid-like protein, mitochondrial, 3.4.21.105, Mitochondrial intramembrane cleaving protease PARL, P-beta, Pbeta, PARL, PSARL | 说明书: |