搜索

购物车()
胎牛血清 移液枪头 PEI DMEM eppendorf
首页> 生物试剂> 免疫检测> 抗体


Osteoprotegerin / OPG Antibody (aa20-37, clone 98A1071)
  • 商城价格 登录后可查看价格
  • 货号 LM17480
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 50 μg
  • 单位 个
  • 储存条件 见详情介绍
  • 现货状态
  • 数量

    - +

    成功收藏产品
  • 立即购买
登录后可见商家信息
热门推荐
商家描述 产品评价(0)

品牌：

Leading Biology

货号：

LM17480

规格：

50 μg

产品官网链接：

产品分类：

单克隆抗体

研究领域：

产品概述：

Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.

来源：

Mouse

靶点/蛋白质：

A peptide corresponding to the amino acids 20-37 TQETFPPKYLHYDEETSH of human OPG was used to immunize mice. The specificity was tested on recombinant OPG by western blot analysis.

特异性：

Human

存储温度：

存储溶液：

应用：

IHC-P (5 μg/ml)

参考文献：

Simonet W.S.,et al.Cell 89:309-319(1997). Yasuda H.,et al.Endocrinology 139:1329-1337(1998). Morinaga T.,et al.Eur. J. Biochem. 254:685-691(1998). Ota T.,et al.Nat. Genet. 36:40-45(2004). Suzuki Y.,et al.Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases.

详情介绍：

Function Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis. Cellular_Location Secreted. Tissue_Location Highly expressed in adult lung, heart, kidney, liver, spleen, thymus, prostate, ovary, small intestine, thyroid, lymph node, trachea, adrenal gland, testis, and bone marrow Detected at very low levels in brain, placenta and skeletal muscle. Highly expressed in fetal kidney, liver and lung

别名：

Tumor necrosis factor receptor superfamily member 11B, Osteoclastogenesis inhibitory factor, Osteoprotegerin, TNFRSF11B, OCIF, OPG

说明书：

返回顶部