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品牌: | Leading Biology | 货号: | LM17477 |
规格: | 100 μg | 产品官网链接: | |
产品分类: | 单克隆抗体 | 研究领域: | |
产品概述: | Nudix hydrolases, such as NUDT5, eliminate toxic nucleotide derivatives from the cell and regulate the levels of important signaling nucleotides and their metabolites (McLennan, 1999 [PubMed 10373642]). | 来源: | mouse |
靶点/蛋白质: | NUDT5 (NP_054861, 120 a.a. ~ 219 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | 特异性: | Human |
存储温度: | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | 存储溶液: | Clear, colorless solution in phosphate buffered saline, pH 7.2. |
应用: | WB~~1:500~1000 | 参考文献: | Suppression of mutagenesis by 8-hydroxy-2'-deoxyguanosine 5'-triphosphate (7,8-dihydro-8-oxo-2'-deoxyguanosine 5'-triphosphate) by human MTH1, MTH2, and NUDT5. Hori M, et al. Free Radic Biol Med, 2010 May 1. PMID 20144704.NUDT5 hydrolyzes oxidized deoxyribonucleoside diphosphates with broad substrate specificity. Kamiya H, et al. DNA Repair (Amst), 2009 Oct 2. PMID 19699693.Molecular mechanism of ADP-ribose hydrolysis by human NUDT5 from structural and kinetic studies. Zha M, et al. J Mol Biol, 2008 Jun 6. PMID 18462755.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.Immunoaffinity profiling of tyrosine phosphorylation in cancer cells. Rush J, et al. Nat Biotechnol, 2005 Jan. PMID 15592455. |
详情介绍: | |||
别名: | ADP-sugar pyrophosphatase, 8-oxo-dGDP phosphatase, Nucleoside diphosphate-linked moiety X motif 5, Nudix motif 5, YSA1H, NUDT5 | 说明书: |