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品牌: | Leading Biology | 货号: | LM17470 |
规格: | 100 μg | 产品官网链接: | |
产品分类: | 单克隆抗体 | 研究领域: | |
产品概述: | This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene. | 来源: | mouse |
靶点/蛋白质: | NTRK2 (AAH31835, 1 a.a. ~ 477 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | 特异性: | Human |
存储温度: | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | 存储溶液: | Clear, colorless solution in phosphate buffered saline, pH 7.2. |
应用: | WB~~1:500~1000 | 参考文献: | 1.Pharmacological characterization of six trkB antibodies reveals a novel class of functional agents for the study of the BDNF receptor.Cazorla M, Arrang JM, Premont J.Br J Pharmacol. 2011 Feb;162(4):947-60. doi: 10.1111/ j.1476-5381. 2010.01094.x. |
详情介绍: | |||
别名: | BDNF/NT-3 growth factors receptor, GP145-TrkB, Trk-B, Neurotrophic tyrosine kinase receptor type 2, TrkB tyrosine kinase, Tropomyosin-related kinase B, NTRK2, TRKB | 说明书: |