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NMNAT2 Antibody (monoclonal) (M01)
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  • 货号 LM17439
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 100 μg
  • 单位 个
  • 储存条件 见详情介绍
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品牌：

Leading Biology

货号：

LM17439

规格：

100 μg

产品官网链接：

产品分类：

单克隆抗体

研究领域：

产品概述：

This gene product belongs to the nicotinamide mononucleotide adenylyltransferase (NMNAT) enzyme family, members of which catalyze an essential step in NAD (NADP) biosynthetic pathway. Unlike the other human family member, which is localized to the nucleus, and is ubiquitously expressed; this enzyme is cytoplasmic, and is predominantly expressed in the brain. Two transcript variants encoding different isoforms have been found for this gene.

来源：

mouse

靶点/蛋白质：

NMNAT2 (NP_055854, 208 a.a. ~ 307 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

特异性：

Human

存储温度：

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

存储溶液：

Clear, colorless solution in phosphate buffered saline, pH 7.2.

应用：

WB~~1:500~1000

参考文献：

Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases. Lau C, et al. J Biol Chem, 2010 Jun 11. PMID 20388704.Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. Rose JE, et al. Mol Med, 2010 Jul-Aug. PMID 20379614.Initial-rate kinetics of human NMN-adenylyltransferases: substrate and metal ion specificity, inhibition by products and multisubstrate analogues, and isozyme contributions to NAD+ biosynthesis. Sorci L, et al. Biochemistry, 2007 Apr 24. PMID 17402747.The DNA sequence and biological annotation of human chromosome 1. Gregory SG, et al. Nature, 2006 May 18. PMID 16710414.Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms. Berger F, et al. J Biol Chem, 2005 Oct 28. PMID 16118205.

详情介绍：

别名：

Nicotinamide mononucleotide adenylyltransferase 2, NMN adenylyltransferase 2, Nicotinate-nucleotide adenylyltransferase 2, NaMN adenylyltransferase 2, NMNAT2, C1orf15, KIAA0479

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