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NME2 Antibody (monoclonal) (M09)
  • 商城价格 登录后可查看价格
  • 货号 LM17437
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 100 μg
  • 单位 个
  • 储存条件 见详情介绍
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品牌：

Leading Biology

货号：

LM17437

规格：

100 μg

产品官网链接：

产品分类：

单克隆抗体

研究领域：

产品概述：

Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by NME1) and 'B' (encoded by this gene) isoforms. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. Co-transcription of this gene and the neighboring upstream gene (NME1) generates naturally-occurring transcripts (NME1-NME2) which encode a fusion protein comprised of sequence sharing identity with each individual gene product.

来源：

mouse

靶点/蛋白质：

NME2 (NP_002503, 51 a.a. ~ 152 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

特异性：

Human, Mouse, Rat

存储温度：

Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.

存储溶液：

Clear, colorless solution in phosphate buffered saline, pH 7.2.

应用：

WB~~1:500~1000

参考文献：

Nme protein family evolutionary history, a vertebrate perspective. Desvignes T, et al. BMC Evol Biol, 2009 Oct 23. PMID 19852809.Identification and functional characterization of cytoplasmic determinants of plasmid DNA nuclear import. Munkonge FM, et al. J Biol Chem, 2009 Sep 25. PMID 19638341.Transglutaminase 2 and nucleoside diphosphate kinase activity are correlated in epithelial membranes and are abnormal in cystic fibrosis. Treharne KJ, et al. FEBS Lett, 2009 Sep 3. PMID 19619546.Role of nm23 in the regulation of cell shape and migration via Rho family GTPase signals. Miyamoto M, et al. Mol Cell Biochem, 2009 Sep. PMID 19381785.NM23H2 inhibits EGF- and Ras-induced proliferation of NIH3T3 cells by blocking the ERK pathway. Lee MY, et al. Cancer Lett, 2009 Mar 18. PMID 19022560.

详情介绍：

别名：

Nucleoside diphosphate kinase B, NDK B, NDP kinase B, C-myc purine-binding transcription factor PUF, Histidine protein kinase NDKB, nm23-H2, NME2, NM23B

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