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品牌: | Leading Biology | 货号: | LM17431 |
规格: | 100 μl | 产品官网链接: | |
产品分类: | 单克隆抗体 | 研究领域: | |
产品概述: | 来源: | Mouse | |
靶点/蛋白质: | 特异性: | Human | |
存储温度: | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | 存储溶液: | |
应用: | WB~~1/500 - 1/2000 | 参考文献: | 1. Mol Cell Biol. 2004 Apr;24(7):3048-56. 2. J Biol Chem. 2004 Oct 15;279(42):44030-8. 3. J Bone Miner Res. 2009 Dec;24(12):2039-49. |
详情介绍: | Function Inhibits NF-kappa-B by complexing with and trapping it in the cytoplasm. However, the unphosphorylated form resynthesized after cell stimulation is able to bind NF-kappa-B allowing its transport to the nucleus and protecting it to further NFKBIA- dependent inactivation. Association with inhibitor kappa B- interacting NKIRAS1 and NKIRAS2 prevent its phosphorylation rendering it more resistant to degradation, explaining its slower degradation. Cellular_Location Cytoplasm. Nucleus Tissue_Location Expressed in all tissues examined. | ||
别名: | NF-kappa-B inhibitor beta, NF-kappa-BIB, I-kappa-B-beta, IkB-B, IkB-beta, IkappaBbeta, Thyroid receptor-interacting protein 9, TR-interacting protein 9, TRIP-9, NFKBIB, IKBB, TRIP9 | 说明书: |