商家描述
产品评价(0)
品牌: | Leading Biology | 货号: | LM17429 |
规格: | 100 μl | 产品官网链接: | |
产品分类: | 单克隆抗体 | 研究领域: | |
产品概述: | EIF2A is a 65-kD protein that catalyzes the formation of puromycin-sensitive 80S preinitiation complexes. | 来源: | Mouse |
靶点/蛋白质: | 特异性: | Human | |
存储温度: | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. | 存储溶液: | |
应用: | E~~1/10000 WB~~1/500 - 1/2000 IHC~~1/200 - 1/1000 | 参考文献: | 1. J Exp Clin Cancer Res. 2012 Aug 19;31:66. 2. Physiol Genomics. 2012 Aug 1;44(15):754-63. |
详情介绍: | Function Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region. Cellular_Location Cytoplasm, cytosol. Nucleus. Note=Cytosolic under unstressed conditions, translocates into the nucleus upon induction by electrophilic agents Tissue_Location Widely expressed. Highest expression in adult muscle, kidney, lung, liver and in fetal muscle | ||
别名: | Nuclear factor erythroid 2-related factor 2, NF-E2-related factor 2, NFE2-related factor 2, HEBP1, Nuclear factor, erythroid derived 2, like 2, NFE2L2, NRF2 | 说明书: |