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NEDD8 Antibody
  • 商城价格 登录后可查看价格
  • 货号 LM17417
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 100 μl
  • 单位
  • 储存条件 见详情介绍
  • 现货状态

  • 数量

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品牌:

Leading Biology

货号:

LM17417

规格:

100 μl

产品官网链接:

产品分类:

单克隆抗体

研究领域:

产品概述:

来源:

Mouse

靶点/蛋白质:

特异性:

Human

存储温度:

Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.

存储溶液:

应用:

E~~1/10000 WB~~1/500 - 1/2000 IHC~~1/500 - 1/2000 IF~~1/200 - 1/1000 FC~~1/200 - 1/400

参考文献:

1. Cell. 2009 Jul 23;138(2):389-403. 2. Biochem Biophys Res Commun. 2009 Apr 10;381(3):443-7.

详情介绍:

Function Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C- APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. Cellular_Location Nucleus. Note=Mainly nuclear Tissue_Location Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes

别名:

NEDD8, Neddylin, Neural precursor cell expressed developmentally down-regulated protein 8, NEDD-8, Ubiquitin-like protein Nedd8, NEDD8

说明书:

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