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品牌: | Leading Biology | 货号: | LM17387 |
规格: | 100 μg | 产品官网链接: | |
产品分类: | 单克隆抗体 | 研究领域: | |
产品概述: | The enzyme mevalonate pyrophosphate decarboxylase catalyzes the conversion of mevalonate pyrophosphate into isopentenyl pyrophosphate in one of the early steps in cholesterol biosynthesis. It decarboxylates and dehydrates its substrate while hydrolyzing ATP. | 来源: | mouse |
靶点/蛋白质: | MVD (NP_002452, 301 a.a. ~ 398 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | 特异性: | Human |
存储温度: | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | 存储溶液: | Clear, colorless solution in phosphate buffered saline, pH 7.2. |
应用: | WB~~1:500~1000 | 参考文献: | Variation at the NFATC2 Locus Increases the Risk of Thiazolinedinedione-Induced Edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) Study. Bailey SD, et al. Diabetes Care, 2010 Jul 13. PMID 20628086.Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. Talmud PJ, et al. Am J Hum Genet, 2009 Nov. PMID 19913121.Human mevalonate diphosphate decarboxylase: characterization, investigation of the mevalonate diphosphate binding site, and crystal structure. Voynova NE, et al. Arch Biochem Biophys, 2008 Dec 1. PMID 18823933.Multiple genetic variants along candidate pathways influence plasma high-density lipoprotein cholesterol concentrations. Lu Y, et al. J Lipid Res, 2008 Dec. PMID 18660489.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070. |
详情介绍: | |||
别名: | Diphosphomevalonate decarboxylase, Mevalonate (diphospho)decarboxylase, MDDase, Mevalonate pyrophosphate decarboxylase, MVD, MPD | 说明书: |