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APOA1 / Apolipoprotein A 1 Antibody
  • 商城价格 登录后可查看价格
  • 货号 LM16488
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 500 μg
  • 单位
  • 储存条件 见详情介绍
  • 现货状态

  • 数量

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品牌:

Leading Biology

货号:

LM16488

规格:

500 μg

产品官网链接:

产品分类:

单克隆抗体

研究领域:

产品概述:

Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility.

来源:

Mouse

靶点/蛋白质:

Recognizes Apolipoprotein A-I (Apo A-I). This product does not cross-react with APO A-II or APO B in competitive RIA.

特异性:

Human

存储温度:

存储溶液:

应用:

IHC-P (10 μg/ml),

参考文献:

Shoulders C.C.,et al.Nucleic Acids Res. 11:2827-2837(1983). Cheung P.,et al.Nucleic Acids Res. 11:3703-3715(1983). Karathanasis S.K.,et al.Proc. Natl. Acad. Sci. U.S.A. 80:6147-6151(1983). Seilhamer J.J.,et al.DNA 3:309-317(1984). Sharpe C.R.,et al.Nucleic Acids Res. 12:3917-3932(1984).

详情介绍:

Function Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. Cellular_Location Secreted. Tissue_Location Major protein of plasma HDL, also found in chylomicrons. Synthesized in the liver and small intestine. The oxidized form at Met-110 and Met-136 is increased in individuals with increased risk for coronary artery disease, such as in carrier of the eNOSa/b genotype and exposure to cigarette smoking It is also present in increased levels in aortic lesions relative to native ApoA-I and increased levels are seen with increasing severity of disease.

别名:

APOA1, ApoA-I, APOAI, Apolipoprotein A-I, Apolipoprotein A1, Apo-AI

说明书:

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