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Glycophorin A / CD235a (Erythrocyte Marker) Antibody
  • 商城价格 登录后可查看价格
  • 货号 LM13389
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 7 ml
  • 单位 个
  • 储存条件 见详情介绍
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品牌：

Leading Biology

货号：

LM13389

规格：

7 ml

产品官网链接：

产品分类：

单克隆抗体

研究领域：

产品概述：

Recognizes a sialoglycoprotein of 39kDa, identified as glycophorin A (GPA). It is present on red blood cells (RBC) and erythroid precursor cells. It has been shown that glycophorin acts as the receptor for Sandei virus and parvovirus. Glycophorins A (GPA) and B (GPB), which are single, trans-membrane sialoglycoproteins. GPA is the carrier of blood group M and N specificities, while GPB accounts for S and U specificities. GPA and GPB provide the cells with a large mucin like surface and it has been suggested this provides a barrier to cell fusion, so minimizing aggregation between red blood cells in the circulation.

来源：

Mouse

靶点/蛋白质：

特异性：

Human

存储温度：

Store at 2 to 8°C.Antibody is stable for 24 months.

存储溶液：

应用：

参考文献：

Andersson, L.C., et al. 1979. Glycophorin A as a cell surface marker of early erythroid differentiation in acute leukemia. Int. J. Cancer 23: 717-720. | Liszka, K., et al., 1983. Glycophorin A expression in malignant hematopoiesis. Am. J. Hematol. 15: 219-226

详情介绍：

Function Glycophorin A is the major intrinsic membrane protein of the erythrocyte. The N-terminal glycosylated segment, which lies outside the erythrocyte membrane, has MN blood group receptors. Appears to be important for the function of SLC4A1 and is required for high activity of SLC4A1. May be involved in translocation of SLC4A1 to the plasma membrane. Is a receptor for influenza virus. Is a receptor for Plasmodium falciparum erythrocyte-binding antigen 175 (EBA-175); binding of EBA-175 is dependent on sialic acid residues of the O-linked glycans. Appears to be a receptor for Hepatitis A virus (HAV). Cellular_Location Cell membrane; Single-pass type I membrane protein Note=Appears to be colocalized with SLC4A1

别名：

Glycophorin-A, MN sialoglycoprotein, PAS-2, Sialoglycoprotein alpha, CD235a, GYPA, GPA

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