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CD44 Antibody (clone IM7, PE, Cy7)
  • 商城价格 登录后可查看价格
  • 货号 LM11693
  • 品牌 Leading Biology ( 经销商 )
  • CAS号 见包装
  • 规格/包装 50 μg
  • 单位 个
  • 储存条件 见详情介绍
  • 现货状态
  • 数量

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品牌：

Leading Biology

货号：

LM11693

规格：

50 μg

产品官网链接：

产品分类：

单克隆抗体

研究领域：

产品概述：

Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events.

来源：

Rat

靶点/蛋白质：

特异性：

Human, Mouse

存储温度：

存储溶液：

应用：

IHC-P (1:50),

参考文献：

Stamenkovic I.,et al.Cell 56:1057-1062(1989). Harn H.-J.,et al.Biochem. Biophys. Res. Commun. 178:1127-1134(1991). Stamenkovic I.,et al.EMBO J. 10:343-348(1991). Dougherty G.J.,et al.J. Exp. Med. 174:1-5(1991). Kugelman L.C.,et al.J. Invest. Dermatol. 99:886-891(1992).

详情介绍：

Function Receptor for hyaluronic acid (HA). Mediates cell-cell and cell-matrix interactions through its affinity for HA, and possibly also through its affinity for other ligands such as osteopontin, collagens, and matrix metalloproteinases (MMPs). Adhesion with HA plays an important role in cell migration, tumor growth and progression. In cancer cells, may play an important role in invadopodia formation. Also involved in lymphocyte activation, recirculation and homing, and in hematopoiesis. Altered expression or dysfunction causes numerous pathogenic phenotypes. Great protein heterogeneity due to numerous alternative splicing and post-translational modification events. Cellular_Location Cell membrane; Single-pass type I membrane protein. Note=Colocalizes with actin in membrane protrusions at wounding edges. Tissue_Location Isoform 10 (epithelial isoform) is expressed by cells of epithelium and highly expressed by carcinomas Expression is repressed in neuroblastoma cells

别名：

CD44, CDW44, CD44 antigen, Cell surface glycoprotein CD44, CSPG8, ECMR-III, Epican, HUTCH-I, LHR, MDU2, MC56, MIC4, Hermes antigen, Hyaluronate receptor, Phagocytic glycoprotein 1, PGP-1, PGP-I, Pgp1, Phagocytic glycoprotein I, MDU3, CD44R, HCELL, He ...

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